1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. 8-Bromoadenosine

8-Bromoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).

For research use only. We do not sell to patients.

8-Bromoadenosine Chemical Structure

8-Bromoadenosine Chemical Structure

CAS No. : 2946-39-6

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10 mM * 1 mL in DMSO
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Based on 1 publication(s) in Google Scholar

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Description

8-Bromoadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

Molecular Weight

346.14

Formula

C10H12BrN5O4

CAS No.
Appearance

Solid

SMILES

O[C@H]1[C@@H](O)[C@H](N2C(Br)=NC3=C2N=CN=C3N)O[C@@H]1CO

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (288.90 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8890 mL 14.4450 mL 28.8900 mL
5 mM 0.5778 mL 2.8890 mL 5.7780 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.68%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8890 mL 14.4450 mL 28.8900 mL 72.2251 mL
5 mM 0.5778 mL 2.8890 mL 5.7780 mL 14.4450 mL
10 mM 0.2889 mL 1.4445 mL 2.8890 mL 7.2225 mL
15 mM 0.1926 mL 0.9630 mL 1.9260 mL 4.8150 mL
20 mM 0.1445 mL 0.7223 mL 1.4445 mL 3.6113 mL
25 mM 0.1156 mL 0.5778 mL 1.1556 mL 2.8890 mL
30 mM 0.0963 mL 0.4815 mL 0.9630 mL 2.4075 mL
40 mM 0.0722 mL 0.3611 mL 0.7223 mL 1.8056 mL
50 mM 0.0578 mL 0.2889 mL 0.5778 mL 1.4445 mL
60 mM 0.0482 mL 0.2408 mL 0.4815 mL 1.2038 mL
80 mM 0.0361 mL 0.1806 mL 0.3611 mL 0.9028 mL
100 mM 0.0289 mL 0.1445 mL 0.2889 mL 0.7223 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
8-Bromoadenosine
Cat. No.:
HY-W013195
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