Bromindione (Synonyms: Fluidane; Halinone)

Cat. No.: HY-B0917 Purity: 98.11%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

Bromindione is a potent, long-acting, inandione-derived, oral anticoagulant compound.

For research use only. We do not sell to patients.

Bromindione Chemical Structure

CAS No. : 1146-98-1

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 27	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 27	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	USD 25	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 35	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 53	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 90	In-stock	Estimated Time of Arrival: December 31
250 mg	USD 190	In-stock	Estimated Time of Arrival: December 31
500 mg		Get quote
1 g		Get quote

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Biological Activity
Purity & Documentation
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Description

Bromindione is a potent, long-acting, inandione-derived, oral anticoagulant compound.

Molecular Weight

301.13

Formula

C₁₅H₉BrO₂

CAS No.

1146-98-1

Appearance

Solid

Color

Light brown to brown

SMILES

O=C1C(C2=CC=C(Br)C=C2)C(C3=C1C=CC=C3)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	2 years
	-20°C	1 year

Solvent & Solubility

In Vitro:

DMSO : 250 mg/mL (830.21 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3208 mL	16.6041 mL	33.2082 mL
5 mM	0.6642 mL	3.3208 mL	6.6416 mL
10 mM	0.3321 mL	1.6604 mL	3.3208 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 6.25 mg/mL (20.76 mM); Clear solution

This protocol yields a clear solution of ≥ 6.25 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (62.5 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 98.11%

Select Batch:

Data Sheet (243 KB) SDS (393 KB)

COA (249 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.3208 mL	16.6041 mL	33.2082 mL	83.0206 mL
	5 mM	0.6642 mL	3.3208 mL	6.6416 mL	16.6041 mL
	10 mM	0.3321 mL	1.6604 mL	3.3208 mL	8.3021 mL
	15 mM	0.2214 mL	1.1069 mL	2.2139 mL	5.5347 mL
	20 mM	0.1660 mL	0.8302 mL	1.6604 mL	4.1510 mL
	25 mM	0.1328 mL	0.6642 mL	1.3283 mL	3.3208 mL
	30 mM	0.1107 mL	0.5535 mL	1.1069 mL	2.7674 mL
	40 mM	0.0830 mL	0.4151 mL	0.8302 mL	2.0755 mL
	50 mM	0.0664 mL	0.3321 mL	0.6642 mL	1.6604 mL
	60 mM	0.0553 mL	0.2767 mL	0.5535 mL	1.3837 mL
	80 mM	0.0415 mL	0.2076 mL	0.4151 mL	1.0378 mL
	100 mM	0.0332 mL	0.1660 mL	0.3321 mL	0.8302 mL

Bromindione Related Classifications

Cardiovascular Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bromindione1146-98-1Fluidane HalinoneOthersInhibitorinhibitorinhibit

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