2. Metabolic Enzyme/Protease
  3. DAGL
  4. DO34 analog

DO34 analog is a triazole DAGL(α) inhibitor extracted from patent WO2017096315 A1, compound 100.

For research use only. We do not sell to patients.

DO34 analog Chemical Structure

DO34 analog Chemical Structure

CAS No. : 2098969-71-0

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Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
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10 mM * 1 mL in DMSO USD 175 In-stock
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10 mg USD 240 In-stock
50 mg USD 750 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

DO34 analog is a triazole DAGL(α) inhibitor extracted from patent WO2017096315 A1, compound 100.

Molecular Weight

531.53

Formula

C26H28F3N5O4
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(N1C(CC2=CC=CC=C2)CN(C(OC(C)(C)C)=O)CC1)N3N=CC(C4=CC=C(OC(F)(F)F)C=C4)=N3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : ≥ 105 mg/mL (197.54 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8814 mL 9.4068 mL 18.8136 mL
5 mM 0.3763 mL 1.8814 mL 3.7627 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.42%

COA (250 KB) LCMS (261 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.8814 mL 9.4068 mL 18.8136 mL 47.0340 mL
5 mM 0.3763 mL 1.8814 mL 3.7627 mL 9.4068 mL
10 mM 0.1881 mL 0.9407 mL 1.8814 mL 4.7034 mL
15 mM 0.1254 mL 0.6271 mL 1.2542 mL 3.1356 mL
20 mM 0.0941 mL 0.4703 mL 0.9407 mL 2.3517 mL
25 mM 0.0753 mL 0.3763 mL 0.7525 mL 1.8814 mL
30 mM 0.0627 mL 0.3136 mL 0.6271 mL 1.5678 mL
40 mM 0.0470 mL 0.2352 mL 0.4703 mL 1.1759 mL
50 mM 0.0376 mL 0.1881 mL 0.3763 mL 0.9407 mL
60 mM 0.0314 mL 0.1568 mL 0.3136 mL 0.7839 mL
80 mM 0.0235 mL 0.1176 mL 0.2352 mL 0.5879 mL
100 mM 0.0188 mL 0.0941 mL 0.1881 mL 0.4703 mL
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DO34 analog Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DO342098969-71-0DO 34DO-34DAGLDiacylglycerol lipaseDAG lipaseDGLInhibitorinhibitorinhibit

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