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Targeted Diversity Library

Cat. No.: HY-L099

MCE Targeted Diversity Library contains 2,208 compounds, covering more than 1000 targets and isoforms, such as GPCRs, Ion channel, variety of kinases, etc. 1-3 compounds with high potency and selectivity were carefully selected for each target and isoform. The bioactivity information of each compound has been clearly reported in the literatures. This library is a concise collection of small molecule compounds with comprehensive target coverage, which can be used for phenotypic screening at low cost.

For pre-dissolved solutions, 10 mM for compounds with the solubility not lower than 10 mM, 2 mM for compounds with solubility between 2 mM and 10 mM, and 3 mg/mL for compounds with unconfirmed molecular weight and solubility not lower than 3 mg/mL.

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Description & Advantages

•   A unique collection of 2,208 bioactive compounds covering more than 1000 targets and isoforms.

•   1-3 compounds with high potency and selectivity were carefully selected for each target and isoform.

•   Target diverse, medicinally active and cell permeable.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

Product Details

Formulation:

A collection of 2,208 Targeted Diversity compounds supplied as pre-dissolved Solutions or Solid.
Solution: 2,176 compounds supplied in 10 mM solution, 31 compounds supplied in 2 mM solution, 1 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode.

Storage:

-80°C

Shipping:

Blue ice or dry ice

Composition

PI3K (40)

CDK (38)

EGFR (25)

HIV (22)

HDAC (18)

VEGFR (18)

Akt (17)

CCR (17)

FGFR (16)

mAChR (16)

CXCR (15)

mGluR (15)

MMP (15)

HSP (14)

IKK (14)

STAT (14)

JAK (13)

PKC (13)

HCV (12)

PARP (12)

COX (11)

ERK (11)

GSK-3 (11)

Raf (11)

MEK (10)

mTOR (10)

PDGFR (10)

JNK (9)

LXR (9)

PI4K (9)

PPAR (9)

DYRK (8)

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  •  Specific Compounds
  •  Quantities
  •  Plate Map
  •  Concentration
  •  Form (Solid or Solution)
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    Product Name:
    Targeted Diversity Library
    Cat. No.:
    HY-L099
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    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack
    • 96-well Plate with Peelable Foil Seal
    • 384-well Microplate with Peelable Foil Seal
    • 96-well Storage Tubes with Rack

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