2. Anti-infection
  3. Bacterial
  4. TBA-7371

TBA-7371 is a potent, noncovalent DprE1 inhibitor. TBA-7371 has potent antitubercular activity .

For research use only. We do not sell to patients.

TBA-7371 Chemical Structure

TBA-7371 Chemical Structure

CAS No. : 1494675-86-3

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 61 In-stock
Solution
10 mM * 1 mL in DMSO USD 61 In-stock
Solid
1 mg USD 28 In-stock
5 mg USD 55 In-stock
10 mg USD 88 In-stock
25 mg USD 165 In-stock
50 mg USD 275 In-stock
100 mg USD 473 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

TBA-7371 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE TBA-7371

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

TBA-7371 is a potent, noncovalent DprE1 inhibitor. TBA-7371 has potent antitubercular activity [1].

IC50 & Target

DprE1[1]
Clinical Trial
Molecular Weight

355.39

Formula

C18H21N5O3
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CN(CC2=NC=NC(OC)=C2C)C3=CC(C)=CN=C31)NCCO
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (70.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8138 mL 14.0691 mL 28.1381 mL
5 mM 0.5628 mL 2.8138 mL 5.6276 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8138 mL 14.0691 mL 28.1381 mL 70.3453 mL
5 mM 0.5628 mL 2.8138 mL 5.6276 mL 14.0691 mL
10 mM 0.2814 mL 1.4069 mL 2.8138 mL 7.0345 mL
15 mM 0.1876 mL 0.9379 mL 1.8759 mL 4.6897 mL
20 mM 0.1407 mL 0.7035 mL 1.4069 mL 3.5173 mL
25 mM 0.1126 mL 0.5628 mL 1.1255 mL 2.8138 mL
30 mM 0.0938 mL 0.4690 mL 0.9379 mL 2.3448 mL
40 mM 0.0703 mL 0.3517 mL 0.7035 mL 1.7586 mL
50 mM 0.0563 mL 0.2814 mL 0.5628 mL 1.4069 mL
60 mM 0.0469 mL 0.2345 mL 0.4690 mL 1.1724 mL
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TBA-7371 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TBA-73711494675-86-3TBA7371TBA 7371BacterialDprE1noncovalentantitubercularantituberculosistuberculosisInhibitorinhibitorinhibit

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