Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH (Synonyms: Fmoc-Ser-(GalNAc(Ac)3-alpha-D)-OH; Fmoc-Ser[GalNAc(Ac)3-α-D]-OH; Fmoc-Ser(Ac3AcNH-α-Gal)-OH)

Name: Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH
Brand: MedChemExpress
SKU: HY-104004
Rating: 4.5 (1 reviews)

Cat. No.: HY-104004 Purity: 98.60%: FAQs
Data Sheet SDS COA Handling Instructions

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Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH is a agent for cancer.

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Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH Chemical Structure

CAS No. : 120173-57-1

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	USD 72	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	USD 72	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 70	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 125	In-stock	Estimated Time of Arrival: December 31
50 mg	USD 185	In-stock	Estimated Time of Arrival: December 31
100 mg	USD 275	In-stock	Estimated Time of Arrival: December 31
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500 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH:

Fmoc-Ser(O-β-D-GalNAc(OAc)3)-OH Get quote

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Description

Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH is a agent for cancer.

Molecular Weight

656.63

Formula

C₃₂H₃₆N₂O₁₃

CAS No.

120173-57-1

Appearance

Solid

Color

White to off-white

SMILES

O=C(N[C@H](C(O)=O)CO[C@@H](O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@@H]1OC(C)=O)[C@@H]1NC(C)=O)OCC2C3=CC=CC=C3C4=CC=CC=C24

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 100 mg/mL (152.29 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.5229 mL	7.6146 mL	15.2293 mL
5 mM	0.3046 mL	1.5229 mL	3.0459 mL
10 mM	0.1523 mL	0.7615 mL	1.5229 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (3.81 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (3.81 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (3.81 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Calculation results:

Working solution concentration: mg/mL

Method for preparing stock solution: mg drug dissolved in μL DMSO (Stock solution concentration: mg/mL).

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).

Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.

If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.

Purity & Documentation

Purity: 98.60%

Select Batch:

Data Sheet (277 KB) SDS (557 KB)

COA (258 KB) HNMR (277 KB) LCMS (1095 KB)

Handling Instructions (2659 KB)

References

[1]. Jorg Eberling, et al. Chemoselective Removal of Protecting Groups from O-Glycosyl Amino Acid and Peptide (Methoxyethoxy)ethyl Esters Using Lipases and Papain. J. Org. Chem., 1996, 61 (8), pp 2638–2646

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.5229 mL	7.6146 mL	15.2293 mL	38.0732 mL
	5 mM	0.3046 mL	1.5229 mL	3.0459 mL	7.6146 mL
	10 mM	0.1523 mL	0.7615 mL	1.5229 mL	3.8073 mL
	15 mM	0.1015 mL	0.5076 mL	1.0153 mL	2.5382 mL
	20 mM	0.0761 mL	0.3807 mL	0.7615 mL	1.9037 mL
	25 mM	0.0609 mL	0.3046 mL	0.6092 mL	1.5229 mL
	30 mM	0.0508 mL	0.2538 mL	0.5076 mL	1.2691 mL
	40 mM	0.0381 mL	0.1904 mL	0.3807 mL	0.9518 mL
	50 mM	0.0305 mL	0.1523 mL	0.3046 mL	0.7615 mL
	60 mM	0.0254 mL	0.1269 mL	0.2538 mL	0.6346 mL
	80 mM	0.0190 mL	0.0952 mL	0.1904 mL	0.4759 mL
	100 mM	0.0152 mL	0.0761 mL	0.1523 mL	0.3807 mL

Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

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Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH (Synonyms: Fmoc-Ser-(GalNAc(Ac)3-alpha-D)-OH; Fmoc-Ser[GalNAc(Ac)3-α-D]-OH; Fmoc-Ser(Ac3AcNH-α-Gal)-OH)

Customer Review

Other Forms of Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH:

Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH Related Antibodies

Featured Recommendations

•Related Small Molecules:

•Related Proteins:

Biological Activity

Purity & Documentation

References

Customer Review

Molarity Calculator

Dilution Calculator

Complete Stock Solution Preparation Table

Fmoc-Ser(O-α-D-GalNAc(OAc)3)-OH Related Classifications

Keywords:

Your Recently Viewed Products:

Customer Review

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