2. Metabolic Enzyme/Protease NF-κB Immunology/Inflammation
  3. Endogenous Metabolite Reactive Oxygen Species
  4. Glutathione oxidized

Glutathione oxidized  (Synonyms: L-Glutathione oxidized; GSSG; Oxiglutatione)

Cat. No.: HY-D0844 Purity: 98.79%
COA Handling Instructions

Molarity Calculator

Glutathione oxidized (L-Glutathione oxidized) is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Glutathione oxidized Chemical Structure

Glutathione oxidized Chemical Structure

CAS No. : 27025-41-8

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 USD 28 In-stock
Solution
10 mM * 1 mL in Water USD 28 In-stock
Solid
100 mg USD 25 In-stock
500 mg USD 50 In-stock
1 g USD 60 In-stock
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10 g   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 4 publication(s) in Google Scholar

Other Forms of Glutathione oxidized:

Glutathione oxidized Related Antibodies

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  • Purity & Documentation

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Description

Glutathione oxidized (L-Glutathione oxidized) is produced by the oxidation of glutathione. Detoxification of reactive oxygen species is accompanied by production of glutathione oxidized. Glutathione oxidized can be used for the research of sickle cells and erythrocytes[1][2].

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Increased efflux of Glutathione oxidized leads to glutathione depletion and may weaken the antioxidant defense of sickle erythrocytes[1].
Glutathione oxidized (400 μM) inhibits epithelial sodium channel activity in primary alveolar epithelial T2 cells[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Glutathione oxidized Related Antibodies
Molecular Weight

612.63

Formula

C20H32N6O12S2
CAS No.
Appearance

Solid

Color

White to off-white

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 250 mg/mL (408.08 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6323 mL 8.1615 mL 16.3231 mL
5 mM 0.3265 mL 1.6323 mL 3.2646 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (163.23 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 98.89%

COA (250 KB) HNMR (278 KB) LCMS (98 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.6323 mL 8.1615 mL 16.3231 mL 40.8077 mL
5 mM 0.3265 mL 1.6323 mL 3.2646 mL 8.1615 mL
10 mM 0.1632 mL 0.8162 mL 1.6323 mL 4.0808 mL
15 mM 0.1088 mL 0.5441 mL 1.0882 mL 2.7205 mL
20 mM 0.0816 mL 0.4081 mL 0.8162 mL 2.0404 mL
25 mM 0.0653 mL 0.3265 mL 0.6529 mL 1.6323 mL
30 mM 0.0544 mL 0.2721 mL 0.5441 mL 1.3603 mL
40 mM 0.0408 mL 0.2040 mL 0.4081 mL 1.0202 mL
50 mM 0.0326 mL 0.1632 mL 0.3265 mL 0.8162 mL
60 mM 0.0272 mL 0.1360 mL 0.2721 mL 0.6801 mL
80 mM 0.0204 mL 0.1020 mL 0.2040 mL 0.5101 mL
100 mM 0.0163 mL 0.0816 mL 0.1632 mL 0.4081 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Glutathione oxidized Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Glutathione oxidized27025-41-8L-Glutathione oxidized GSSG OxiglutationeEndogenous MetaboliteReactive Oxygen Speciessickle cellerythrocyteglutathioneROSDMNQInhibitorinhibitorinhibit

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