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  4. Hexylene glycol

Hexylene glycol  (Synonyms: 2-Methyl-2,4-pentanediol; MPD)

Cat. No.: HY-B0903 Purity: ≥98.0%
SDS COA Handling Instructions Technical Support

Hexylene glycol is a low molecular weight surfactant with antimicrobial properties. Hexylene glycol is widely used in industrial chemicals and cosmetics.

For research use only. We do not sell to patients.

Hexylene glycol Chemical Structure

Hexylene glycol Chemical Structure

CAS No. : 107-41-5

Size Price Stock Quantity
Liquid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Liquid
100 mg In-stock
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Hexylene glycol:

Hexylene glycol Related Antibodies

Top Publications Citing Use of Products

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Hexylene glycol is a low molecular weight surfactant with antimicrobial properties. Hexylene glycol is widely used in industrial chemicals and cosmetics[1][2].

In Vitro

Hexylene glycol at 10% and 30% concentrations killed Candida albicans, Staphylococcus aureus, Staphylococcus epidermidis, Group A Streptococcus, Streptococcus parvus, and Escherichia coli in fresh tryptone agar within 20 hours. Hexylene glycol at 5% concentration showed some antimicrobial activity, but hexylene glycol at 1% concentration had no effect[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Hexylene glycol Related Antibodies
Clinical Trial
Molecular Weight

118.18

Formula

C6H14O2
CAS No.
Appearance

Liquid (Density: 0.925 g/cm3)

Color

Colorless to light yellow

SMILES

CC(O)(C)CC(O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (846.17 mM; Need ultrasonic)

DMSO : ≥ 100 mg/mL (846.17 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 8.4617 mL 42.3083 mL 84.6167 mL
5 mM 1.6923 mL 8.4617 mL 16.9233 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (21.15 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL (21.15 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (846.17 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 8.4617 mL 42.3083 mL 84.6167 mL 211.5417 mL
5 mM 1.6923 mL 8.4617 mL 16.9233 mL 42.3083 mL
10 mM 0.8462 mL 4.2308 mL 8.4617 mL 21.1542 mL
15 mM 0.5641 mL 2.8206 mL 5.6411 mL 14.1028 mL
20 mM 0.4231 mL 2.1154 mL 4.2308 mL 10.5771 mL
25 mM 0.3385 mL 1.6923 mL 3.3847 mL 8.4617 mL
30 mM 0.2821 mL 1.4103 mL 2.8206 mL 7.0514 mL
40 mM 0.2115 mL 1.0577 mL 2.1154 mL 5.2885 mL
50 mM 0.1692 mL 0.8462 mL 1.6923 mL 4.2308 mL
60 mM 0.1410 mL 0.7051 mL 1.4103 mL 3.5257 mL
80 mM 0.1058 mL 0.5289 mL 1.0577 mL 2.6443 mL
100 mM 0.0846 mL 0.4231 mL 0.8462 mL 2.1154 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Hexylene glycol Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Hexylene glycol107-41-52-Methyl-2,4-pentanediol MPDBiochemical Assay ReagentsBacterialInhibitorinhibitorinhibit

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