2. Others GPCR/G Protein Neuronal Signaling
  3. Biochemical Assay Reagents mAChR
  4. Methscopolamine bromide

Methscopolamine bromide  (Synonyms: (-)-Scopolamine methyl bromide; Hyoscine methyl bromide)

Cat. No.: HY-B0344 Purity: 99.81%
COA Handling Instructions

Molarity Calculator

Methscopolamine Bromide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

Methscopolamine bromide Chemical Structure

Methscopolamine bromide Chemical Structure

CAS No. : 155-41-9

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 106 In-stock
Solution
10 mM * 1 mL in DMSO USD 106 In-stock
Solid
100 mg USD 96 In-stock
500 mg USD 240 In-stock
1 g   Get quote  
5 g   Get quote  

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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

Methscopolamine bromide Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Methscopolamine bromide

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  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Methscopolamine Bromide is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Molecular Weight

398.29

Formula

C18H24BrNO4
CAS No.
Appearance

Solid

SMILES

C[N+]1([C@@H]2[C@H](O3)[C@H]3[C@H]1C[C@@H](OC([C@@H](C4=CC=CC=C4)CO)=O)C2)C.[Br-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (125.54 mM; Need ultrasonic)

DMSO : ≥ 34 mg/mL (85.36 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5107 mL 12.5537 mL 25.1073 mL
5 mM 0.5021 mL 2.5107 mL 5.0215 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 2.5 mg/mL (6.28 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
  • Protocol 2

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 2.5 mg/mL (6.28 mM); Clear solution

    This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

    Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.81%

COA (254 KB) LCMS (87 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 2.5107 mL 12.5537 mL 25.1073 mL 62.7683 mL
5 mM 0.5021 mL 2.5107 mL 5.0215 mL 12.5537 mL
10 mM 0.2511 mL 1.2554 mL 2.5107 mL 6.2768 mL
15 mM 0.1674 mL 0.8369 mL 1.6738 mL 4.1846 mL
20 mM 0.1255 mL 0.6277 mL 1.2554 mL 3.1384 mL
25 mM 0.1004 mL 0.5021 mL 1.0043 mL 2.5107 mL
30 mM 0.0837 mL 0.4185 mL 0.8369 mL 2.0923 mL
40 mM 0.0628 mL 0.3138 mL 0.6277 mL 1.5692 mL
50 mM 0.0502 mL 0.2511 mL 0.5021 mL 1.2554 mL
60 mM 0.0418 mL 0.2092 mL 0.4185 mL 1.0461 mL
80 mM 0.0314 mL 0.1569 mL 0.3138 mL 0.7846 mL
H2O 100 mM 0.0251 mL 0.1255 mL 0.2511 mL 0.6277 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Methscopolamine bromide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Methscopolamine155-41-9(-)-Scopolamine methylHyoscine methylBiochemical Assay ReagentsmAChRMuscarinic acetylcholine receptorbiochemical assayreagentInhibitorinhibitorinhibit

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