2-(2-Phenylethyl)chromone (Synonyms: Flidersiachromone)

Cat. No.: HY-N8220 Purity: 99.94%: Data Sheet
SDS

COA
Handling Instructions Technical Support

Solubility

In Vivo Dissolution Calculator

2-(2-Phenylethyl)chromone (Flidersiachromone) is one of 2-(2-phenylethyl)chromones that can be found in Chinese eaglewood from Aquilaria sinensis.

For research use only. We do not sell to patients.

2-(2-Phenylethyl)chromone Chemical Structure

CAS No. : 61828-53-3

Size	Price	Stock	Quantity
5 mg	USD 90	In-stock	Estimated Time of Arrival: April 7
10 mg	USD 145	In-stock	Estimated Time of Arrival: April 7
25 mg	USD 250	In-stock	Estimated Time of Arrival: April 7
50 mg	USD 350	In-stock	Estimated Time of Arrival: April 7
100 mg		Get quote
200 mg		Get quote

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Description

2-(2-Phenylethyl)chromone (Flidersiachromone) is one of 2-(2-phenylethyl)chromones that can be found in Chinese eaglewood from Aquilaria sinensis^[1].

Molecular Weight

250.29

Formula

C₁₇H₁₄O₂

CAS No.

61828-53-3

Appearance

Solid

Color

Off-white to gray

SMILES

O=C1C=C(CCC2=CC=CC=C2)OC3=CC=CC=C13

Structure Classification

Ketones, Aldehydes, Acids

Initial Source

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (399.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.9954 mL	19.9768 mL	39.9537 mL
5 mM	0.7991 mL	3.9954 mL	7.9907 mL
10 mM	0.3995 mL	1.9977 mL	3.9954 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (9.99 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (9.99 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil
Solubility: ≥ 2.5 mg/mL (9.99 mM); Clear solution

This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

DMSO +

Tween-80 +

Saline

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.

The co-solvents required include: DMSO, PEG300/PEG400, Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Purity & Documentation

Purity: 99.94%

Select Batch:

Data Sheet (271 KB) SDS (252 KB)

COA (247 KB) HNMR (244 KB) RP-HPLC (252 KB) LCMS (93 KB)

Handling Instructions (2659 KB)

References

[1]. Chun-Ge Li, et al. Antioxidative 2-(2-phenylethyl)chromones in Chinese eaglewood from Aquilaria sinensis. J Asian Nat Prod Res. 2020 Jul;22(7):639-646. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.9954 mL	19.9768 mL	39.9537 mL	99.8841 mL
	5 mM	0.7991 mL	3.9954 mL	7.9907 mL	19.9768 mL
	10 mM	0.3995 mL	1.9977 mL	3.9954 mL	9.9884 mL
	15 mM	0.2664 mL	1.3318 mL	2.6636 mL	6.6589 mL
	20 mM	0.1998 mL	0.9988 mL	1.9977 mL	4.9942 mL
	25 mM	0.1598 mL	0.7991 mL	1.5981 mL	3.9954 mL
	30 mM	0.1332 mL	0.6659 mL	1.3318 mL	3.3295 mL
	40 mM	0.0999 mL	0.4994 mL	0.9988 mL	2.4971 mL
	50 mM	0.0799 mL	0.3995 mL	0.7991 mL	1.9977 mL
	60 mM	0.0666 mL	0.3329 mL	0.6659 mL	1.6647 mL
	80 mM	0.0499 mL	0.2497 mL	0.4994 mL	1.2486 mL
	100 mM	0.0400 mL	0.1998 mL	0.3995 mL	0.9988 mL

2-(2-Phenylethyl)chromone Related Classifications

Others

Keywords:

2-(2-Phenylethyl)chromone61828-53-3FlidersiachromoneOthersAquilariasinensisInhibitorinhibitorinhibit

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2-(2-Phenylethyl)chromone (Synonyms: Flidersiachromone)

2-(2-Phenylethyl)chromone Related Antibodies

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