2. Neuronal Signaling
  3. Monoamine Oxidase
  4. RS 8359

RS 8359 is a selective and reversible MAO-A inhibitor, with antidepressant activity.

For research use only. We do not sell to patients.

RS 8359 Chemical Structure

RS 8359 Chemical Structure

CAS No. : 105365-76-2

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 242 In-stock
Solution
10 mM * 1 mL in DMSO USD 242 In-stock
Solid
5 mg USD 220 In-stock
10 mg USD 350 In-stock
25 mg USD 700 In-stock
50 mg USD 1125 In-stock
100 mg USD 1800 In-stock
200 mg   Get quote  
500 mg   Get quote  

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RS 8359 Related Antibodies

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Description

RS 8359 is a selective and reversible MAO-A inhibitor, with antidepressant activity.

In Vivo

RS 8359 shows relatively little effect upon blood pressure when administered together with tyramine. RS-8359 shows little affinity for the common central nervous system receptors and little anticholinergic effect[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

252.27

Formula

C14H12N4O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC1C2=NC=NC(NC3=CC=C(C#N)C=C3)=C2CC1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (198.20 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9640 mL 19.8200 mL 39.6401 mL
5 mM 0.7928 mL 3.9640 mL 7.9280 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.9640 mL 19.8200 mL 39.6401 mL 99.1002 mL
5 mM 0.7928 mL 3.9640 mL 7.9280 mL 19.8200 mL
10 mM 0.3964 mL 1.9820 mL 3.9640 mL 9.9100 mL
15 mM 0.2643 mL 1.3213 mL 2.6427 mL 6.6067 mL
20 mM 0.1982 mL 0.9910 mL 1.9820 mL 4.9550 mL
25 mM 0.1586 mL 0.7928 mL 1.5856 mL 3.9640 mL
30 mM 0.1321 mL 0.6607 mL 1.3213 mL 3.3033 mL
40 mM 0.0991 mL 0.4955 mL 0.9910 mL 2.4775 mL
50 mM 0.0793 mL 0.3964 mL 0.7928 mL 1.9820 mL
60 mM 0.0661 mL 0.3303 mL 0.6607 mL 1.6517 mL
80 mM 0.0496 mL 0.2478 mL 0.4955 mL 1.2388 mL
100 mM 0.0396 mL 0.1982 mL 0.3964 mL 0.9910 mL
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RS 8359 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RS 8359105365-76-2RS8359RS-8359Monoamine OxidaseMAOInhibitorinhibitorinhibit

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