2. Signaling Pathways
  3. Anti-infection
  4. CMV

CMV

Cytomegalovirus

CMV

Related Products

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Cytomegalovirus (CMV) is a double-stranded DNA virus and is a member of the ubiquitous family of herpesviruses. Cytomegaloviruses escape immunological clearance and persist throughout life in the infected host. Yet, the stability of the balance of this virus-host interaction is dependent upon the state of the cellular immune response, and usually requires the function of specific CD8 T lymphocytes.

Human cytomegalovirus is a member of the viral family known as herpesviruses, Herpesviridae, or human herpesvirus-5 (HHV-5). Human cytomegalovirus infections commonly are associated with the salivary glands. CMV infection may be asymptomatic in healthy people, but it can be life-threatening in an immunocompromised patient. Congenital cytomegalovirus infection can cause morbidity and even death. After infection, CMV often remains latent, but it can reactivate at any time. Eventually, it causes mucoepidermoid carcinoma, and it may be responsible for prostate cancer.

CMV Related Products (59):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-114005
    SB-734117
    		Inhibitor
    SB-734117 is a human cytomegalovirus (HCMV) replication inhibitor that prevents CREB and histone H3 post-translational modifications.
    SB-734117
  • HY-160917
    BAY-43-9695
    		Inhibitor
    BAY-43-9695 is a nonnucleosidic with activity against human cytomegalovirus (hCMV) with IC50 of 0.95 and 1.1 μM, using the FACS and PRA methodes. BAY-43-9695 inhibits the HCMV replication with and without presence of serum proteins, with IC50 of 0.53 and 8.42 μM. BAY-43-9695 is the metabolite of Tomeglovir (BAY38-4766) (HY-108261).
    BAY-43-9695
  • HY-A0032S
    Valganciclovir-d5 TFA
    Valganciclovir-d5 (TFA) is the deuterium labeled Valganciclovir TFA[1]. Valganciclovir, the L-valyl ester of ganciclovir, is actually a proagent for ganciclovir. Valganciclovir is an antiviral medication used to treat cytomegalovirus infections[2][3][4].
    Valganciclovir-d<sub>5</sub> TFA
  • HY-A0032AR
    Valganciclovir hydrochloride (Standard)
    		Inhibitor
    Valganciclovir (hydrochloride) (Standard) is the analytical standard of Valganciclovir (hydrochloride). This product is intended for research and analytical applications. Valganciclovir hydrochloride is an orally active antiviral agent. Valganciclovir hydrochloride can inhibit the growth of adenoviruses and have a protective effect on immunosuppressed hamsters. Valganciclovir hydrochloride can be used for the research of Cytomegalovirus.
    Valganciclovir hydrochloride (Standard)
  • HY-41343
    Triacetyl-ganciclovir
    		Inhibitor
    Triacetyl-ganciclovir is a Ganciclovir derivative. Ganciclovir is an orally active antiviral agent with activity against cytomegalovirus (CMV).
    Triacetyl-ganciclovir
  • HY-105098
    Lobucavir
    		Inhibitor
    Lobucavir (BMS-180194; SQ 34514), a nucleoside analogue, is an antiviral agent. Lobucavir shows a broad spectrum of activity against HBV, HIV/AIDS, and α, β, and γ herpes viruses including CMV, herpes-simplex, varicella-zoster, and Epstein-Barr virus.
    Lobucavir
  • HY-167911
    Cidofovir sodium
    		Inhibitor
    Cidofovir sodium is an acyclic monophosphate nucleotide analogue and CMV inhibitor with antiviral activity. Cidofovir sodium inhibits cytomegalovirus (CMV) replication by selectively inhibiting viral DNA polymerase. Cidofovir sodium induces apoptosis and can be used in studies of AIDS cytomegalovirus retinitis, herpes, and cancer. Cidofovir sodium also has anti-orthopoxvirus and anti-variola activities.
    Cidofovir sodium
  • HY-N1067R
    Xanthohumol (Standard)
    		Inhibitor
    Xanthohumol (Standard) is the analytical standard of Xanthohumol. This product is intended for research and analytical applications. Xanthohumol is one of the principal flavonoids isolated from hops, the inhibitor of diacylglycerol acetyltransferase (DGAT), COX-1 and COX-2, and shows anti-cancer and anti-angiogenic activities. Xanthohumol also has antiviral activity against bovine viral diarrhea virus (BVDV), rhinovirus, HSV-1, HSV-2 and cytomegalovirus (CMV).
    Xanthohumol (Standard)
  • HY-128370
    Calcium trinatrium diethylenetriaminepentaacetic acid hydrate
    		Inhibitor ≥98.0%
    Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) is a metal chelator and a useful antidote (such as acute cadmium intoxication). Diethylenetriaminepentaacetic acid calcium trisodium salt hydrate is a nontoxic inhibitor of CMV replication.
    Calcium trinatrium diethylenetriaminepentaacetic acid hydrate
  • HY-146270
    pUL89 Endonuclease-IN-1
    		Inhibitor
    pUL89 Endonuclease-IN-1 (Compound 13d) is a potent inhibitor of human cytomegalovirus (HCMV) pUL89 endonuclease with the IC50 value of 0.88 μM and has antiviral activitiy.
    pUL89 Endonuclease-IN-1
  • HY-159737
    Rociclovir
    		Inhibitor
    Rociclovir (HOE 602) is an acyclic nucleoside derivative. Rociclovir protects mice against HSV and MCMV infections, but lacks antiviral activity in cell cultures.
    Rociclovir
  • HY-13637R
    Ganciclovir (Standard)
    		Inhibitor
    Ganciclovir (Standard) is the analytical standard of Ganciclovir. This product is intended for research and analytical applications. Ganciclovir (BW 759), a nucleoside analogue, is an orally active antiviral agent with activity against CMV. Ganciclovir also has activity in vitro against members of the herpes group and some other DNA viruses. Ganciclovir inhibits the in vitro replication of human herpes viruses (HSV 1 and 2, CMV) and adenovirus serotypes 1, 2, 4, 6, 8, 10, 19, 22 and 28. Ganciclovir has an IC50 of 5.2 μM for feline herpesvirus type-1 (FHV-1) and can diffuse into the brain.
    Ganciclovir (Standard)
  • HY-17438R
    Cidofovir (Standard)
    		Inhibitor
    Cidofovir (Standard) is the analytical standard of Cidofovir. This product is intended for research and analytical applications. Cidofovir (GS 0504) is an acyclic monophosphate nucleotide analogue and CMV inhibitor with antiviral activity. Cidofovir inhibits cytomegalovirus (CMV) replication by selectively inhibiting viral DNA polymerase. Cidofovir induces apoptosis and can be used in studies of AIDS cytomegalovirus retinitis, herpes, and cancer. Cidofovir also has anti-orthopoxvirus and anti-variola activities.
    Cidofovir (Standard)
  • HY-16305R
    Maribavir (Standard)
    		Inhibitor
    Maribavir (Standard) is the analytical standard of Maribavir. This product is intended for research and analytical applications. Maribavir is a potent inhibitor of histone phosphorylation catalyzed by wild-type pUL97 in vitro, with an IC50 of 3 nM. Maribavir has potent antiviral activity against HCMV and Epstein-Barr virus (EBV).
    Maribavir (Standard)
  • HY-15233R
    Letermovir (Standard)
    		Inhibitor
    Letermovir (Standard) is the analytical standard of Letermovir. This product is intended for research and analytical applications. Letermovir (AIC246) is a potent inhibitor of CMV, which targets the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors.
    Letermovir (Standard)
  • HY-A0032
    Valganciclovir
    		Inhibitor
    Valganciclovir, the L-valyl ester of ganciclovir, is actually a prodrug for ganciclovir.
    Valganciclovir
  • HY-103365
    BX-513 hydrochloride
    		Agonist
    BX-513 hydrochloride (VUF 2274 hydrochloride)is a novel inverse agonists acting on human cytomegalovirus (HCMV)-encoded receptor US28 with the IC50 of 4.9 μM. BX-513 hydrochloride can be used for study of viral infection.
    BX-513 hydrochloride
  • HY-17438A
    Cidofovir dihydrate
    		Inhibitor
    Cidofovir (GS 0504; HPMPC; (S)-HPMPC) dihydrate is an acyclic monophosphate nucleotide analogue and CMV inhibitor with antiviral activity. Cidofovir dihydrate inhibits cytomegalovirus (CMV) replication by selectively inhibiting viral DNA polymerase. Cidofovir dihydrate induces apoptosis and can be used in studies of AIDS cytomegalovirus retinitis, herpes, and cancer. Cidofovir dihydrate also has anti-orthopoxvirus and anti-variola activities.
    Cidofovir dihydrate
  • HY-13578R
    Brivudine (Standard)
    		Inhibitor
    Brivudine (Standard) is the analytical standard of Brivudine. This product is intended for research and analytical applications. Brivudine is a thymidine analogue with antiviral activity, indicated for the early treatment of acute herpes zoster.
    Brivudine (Standard)