2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Enolase
  5. Enolase Inhibitor

Enolase Inhibitor

Enolase Inhibitors (7):

Cat. No. Product Name Effect Purity
  • HY-15858
    AP-III-a4
    		Inhibitor 99.87%
    AP-III-a4 (ENOblock) is a nonsubstrate analogue enolase inhibitor with an IC50 of 0.576 uM. AP-III-a4 can be used for the research of cancer and diabetic.
  • HY-141412
    D-(-)-3-Phosphoglyceric acid disodium
    		Inhibitor ≥98.0%
    D-(-)-3-Phosphoglyceric acid (3-Phospho-D-glyceric acid) disodium is an important intermediate in the enzyme-catalyzed glycolysis process. D-(-)-3-Phosphoglyceric acid disodium competitively inhibits yeast enolase (enolase). D-(-)-3-Phosphoglyceric acid disodium can regulate the activity of phosphoglycerate dehydrogenase (PHGDH) to modulate p53 protein and apoptosis.
  • HY-131904
    POMHEX
    		Inhibitor 99.77%
    POMHEX, a racemic mixture and a cell-permeable pivaloyloxymethyl (POM) proagent of HEX, is a potent, ENO2-specific inhibitor of enolase. POMHEX exhibits low-nanomolar potency against ENO1-deleted cells in vitro and is capable of eradicating ENO1-deleted xenografted tumours in vivo. POMHEX is a potent glycolysis inhibitor.
  • HY-15858A
    AP-III-a4 hydrochloride
    		Inhibitor 98.77%
    AP-III-a4 (ENOblock) hydrochloride is a nonsubstrate analogue enolase inhibitor with an IC50 of 0.576 uM. AP-III-a4 hydrochloride can be used for the research of cancer and diabetic.
  • HY-117778
    SF2312
    		Inhibitor
    SF2312, a natural phosphonate antibiotic (Antibiotic), is a highly potent Enolase inhibitor with IC50s of 37.9 nM and 42.5 nM for human recombinant ENO1 and ENO2, respectively. SF2312 is active against bacteria under anaerobic conditions.
  • HY-131904A
    Hex
    		Inhibitor 99.96%
    Hex is an enolase inhibitor, with Ki values of 74.4 nM and 269.4 nM for ENO2 and ENO1, respectively.
  • HY-117778B
    SF2312 ammonium
    		Inhibitor ≥98.0%
    SF2312 ammonium is the ammonium form of SF2312. SF2312 is a phosphonate antibiotic and enolase inhibitor. SF2312 can be isolated from actinomycete Micromonospora, which is active under anaerobic conditions. SF2312 is selectively toxic to ENO1-deleted glioma cells.