2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

Related Products

PDF 48.35 MB

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-113161S1
    L-Octanoylcarnitine-d9
    L-Octanoylcarnitine-d9 is deuterium labeled L-Octanoylcarnitine. L-Octanoylcarnitine is a plasma metabolite and a physiologically active form of octanoylcarnitine. L-Octanoylcarnitine can be used for the research of breast cancer.
    .
    L-Octanoylcarnitine-d<sub>9</sub>
  • HY-W339816
    (S,R)-Bis(monomyristoylglycero)phosphate ammonium
    (S,R)-Bis(monomyristoylglycero)phosphate ammonium actively contributes to cargo sorting by promoting the degradation and sorting of lipids, and it plays a critical role in the sorting of polyunsaturated fatty acids (PUFAs) within acidic organelles. This phospholipid features two phosphate-linked glycerol molecules arranged in a unique sn-1 glycerophospho-sn-1′ glycerol stereoconformation, with each glycerol molecule esterified to a myristic acid. Typically, it is found in the intraluminal vesicles (ILVs) of late endosomes and lysosomes.
    (S,R)-Bis(monomyristoylglycero)phosphate ammonium
  • HY-W507009
    L-Arginyl-L-alanine
    L-Arginyl-L-alanine is a dipeptide, is a vascular smooth muscle-derived relaxing factor. L-Arginyl-L-alanine increases the smooth muscle levels of cyclic GMP and nitrite in endothelium-denuded arterial rings.
    L-Arginyl-L-alanine
  • HY-B0275R
    Oxytetracycline (Standard)
    Oxytetracycline (Standard) is the analytical standard of Oxytetracycline. This product is intended for research and analytical applications. Oxytetracycline is an antibiotic belonging to the tetracycline class. Oxytetracycline potent inhibits Gram-negative and Gram-positive bacteria. Oxytetracycline is a protein synthesis inhibitor and prevents the binding from aminoacil-tRNA to the complex m-ribosomal RNA. Oxytetracycline also possesses anti-HSV-1 activity.
    Oxytetracycline (Standard)
  • HY-139101
    Guanosine 5'-triphosphate-5'-adenosine
    Guanosine 5'-triphosphate-5'-adenosine (GpppA), a 5′ cap analog, can be used for RNA synthesis in vitro. Guanosine 5'-triphosphate-5'-adenosine is a fluorescent substrate analog.
    Guanosine 5'-triphosphate-5'-adenosine
  • HY-101240
    Propranolol glycol
    Propranolol glycol is a metabolite of propranolol (HY-B0573B). Propranolol glycol shows instantaneous anticonvulsant activity.
    Propranolol glycol
  • HY-W750600
    Acetonitrile-15N
    Acetonitrile-15N (Methyl cyanide-15N) is a stable isotope labeled organic compound with important applications in metabolic research and molecular labeling. Acetonitrile-15N is used in biolabeling experiments to track metabolic pathways and help understand the chemical reaction mechanisms in organisms. Acetonitrile-15N is also widely used in environmental science to study the migration and transformation processes of pollutants.
    Acetonitrile-<sup>15</sup>N
  • HY-W997836
    4-Amino-3-hydroxyphenylalanine
    4-Amino-3-hydroxyphenylalanine (4-AHP) is a photodegradation product of Eumelanin. 4-Amino-3-hydroxyphenylalanine can be used for research of melanomagenesis in the skin and age-related macular degeneration.
    4-Amino-3-hydroxyphenylalanine
  • HY-W654020
    Propyl paraben-13C6
    Propyl paraben-13C6 (Propyl parahydroxybenzoate-13C6) is 13C labeled Propylparaben. Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods. Propylparaben disrupts follicular growth and steroidogenic function by altering cell cycle, apoptosis and steroidogenic pathways. Propylparaben also reduced sperm count and motility in rats.
    Propyl paraben-<sup>13</sup>C<sub>6</sub>
  • HY-168373
    1-Stearoyl-2-Eicosapentaenoyl-sn-glycero-3-PC
    1-Stearoyl-2-eicosapentaenoyl-sn-glycero-3-PC is a phospholipid that can be found in human red blood cells (RBCs).
    1-Stearoyl-2-Eicosapentaenoyl-sn-glycero-3-PC
  • HY-W698343
    NG-Hydroxy-L-arginine acetate
    NG-Hydroxy-L-arginine acetate (NOHA acetate) serves as a physiological inhibitor of arginase, playing a crucial role in the conversion of arginine to nitric oxide and citrulline by nitric oxide synthase.
    NG-Hydroxy-L-arginine acetate
  • HY-W016498R
    Paraxanthine (Standard)
    Paraxanthine (Standard) is the analytical standard of Paraxanthine. This product is intended for research and analytical applications. Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels.
    Paraxanthine (Standard)
  • HY-18258R
    Berberine (chloride) (Standard)
    Berberine (chloride) (Standard) is the analytical standard of Berberine (chloride). This product is intended for research and analytical applications. Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties.
    Berberine (chloride) (Standard)
  • HY-78096
    O-Deshydroxyethyl bosentan
    O-Deshydroxyethyl bosentan is a metabolite of Bosentan (HY-A0013), which is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors.
    O-Deshydroxyethyl bosentan
  • HY-W106641
    (Z)-7-Dodecen-1-ol
    (Z)-7-Dodecen-1-ol inhibits the effect of the attractant Z-7-dodecen-1-yl acetate.
    (Z)-7-Dodecen-1-ol
  • HY-168360
    Bufotenidine iodide
    Bufotenidine iodide is a component found in toad venom and belongs to the indole alkaloid class.
    Bufotenidine iodide
  • HY-113018
    Ibuprofen acyl-β-D-glucuronide
    Ibuprofen acyl-β-D-glucuronide (Ibuprofen glucuronide) is a selective TRPA1 antagonis. Ibuprofen acyl-β-D-glucuronide reduces AITC-evoked calcium response with an IC50 value of 60μM.
    Ibuprofen acyl-β-D-glucuronide
  • HY-17438A
    Cidofovir dihydrate
    Cidofovir (GS 0504; HPMPC; (S)-HPMPC) dihydrate is an acyclic monophosphate nucleotide analogue and CMV inhibitor with antiviral activity. Cidofovir dihydrate inhibits cytomegalovirus (CMV) replication by selectively inhibiting viral DNA polymerase. Cidofovir dihydrate induces apoptosis and can be used in studies of AIDS cytomegalovirus retinitis, herpes, and cancer. Cidofovir dihydrate also has anti-orthopoxvirus and anti-variola activities.
    Cidofovir dihydrate
  • HY-B0251S1
    Eplerenone-13C,d3
    		Inhibitor
    Eplerenone-13C,d3 (Epoxymexrenone-13C,d3) is 13C labeled Eplerenone. Eplerenone (Epoxymexrenone) is a selective, highly specific and orally active aldosterone blocker (SAB). Eplerenone also is a selective mineralocorticoid receptor antagonist (MRA) with IC50 value of 0.081 μM. Eplerenone can be used for the research of hypertension, atherosclerosis, chronic systolic heart failure (HF) and cardiovascular (CV).
    Eplerenone-<sup>13</sup>C,d<sub>3</sub>
  • HY-W753582
    1-Methyl-2-azaadamantane-N-oxyl
    1-Methyl-2-azaadamantane-N-oxyl (1-Me-AZADO), a less sterically hindered nitroxyl radical renowned for its stability and outstanding catalytic performance.
    1-Methyl-2-azaadamantane-N-oxyl
Cat. No. Product Name / Synonyms Application Reactivity