2. Signaling Pathways
  3. Others
  4. Others
  5. Others Inhibitor

Others Inhibitor

Others Inhibitors (1187):

Cat. No. Product Name Effect Purity
  • HY-163541
    SMS121
    		Inhibitor 98.75%
    SMS121 is a CD36 inhibitor. By targeting the lipid uptake protein CD36, SMS121 blocks the pathway of fatty acid entry into AML cells to reduce the uptake of fatty acids by AML cells, thereby reducing the activity of these cells. SMS121 can be used to study acute myeloid leukemia (AML).
  • HY-111374
    NMDI14
    		Inhibitor 99.76%
    NMDI14 is a nonsense mediated RNA decay (NMD) inhibitor. NMDI14 disrupts the SMG7-UPF1 interactions and inhibits NMD.
  • HY-15680
    O-Propargyl-Puromycin
    		Inhibitor 98.74%
    O-Propargyl-Puromycin, an alkyne analog of puromycin, is a potent protein synthesis inhibitor. O-Propargyl-Puromycin is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • HY-19332
    Kifunensine
    		Inhibitor 99.87%
    Kifunensine, a potent and selective inhibitor of class I α-mannosidases isolated from Actinomycete, prevents α-mannosidases I from trimming mannose residues on glycoproteins. Kifunensine inhibits ERAD.
  • HY-W010342
    6-Aminonicotinamide
    		Inhibitor 99.95%
    6-Aminonicotinamide, a potent antimetabolite of nicotinamide, is competitive NADP+-dependent enzyme glucose-6-phosphate dehydrogenase (G6PD) inhibitor (Ki=0.46 μM). 6-Aminonicotinamide resultis ATP depletion and synergizes with DNA-crosslinking chemotherapy agents, such as Cisplatin, in killing cancer cells.
  • HY-17511
    Potassium oxonate
    		Inhibitor 99.94%
    Potassium oxonate (Potassium azaorotate) is a uricase inhibitor that inhibits the phosphorylation of 5-FU to 5-fluorouridine-5'-monophosphate.
  • HY-129389
    Benzyl-α-GalNAc
    		Inhibitor 99.95%
    Benzyl-α-GalNAc is a potent O-glycosylation inhibitor. Benzyl-α-GalNAc effectively inhibits the proliferation and activation of LX-2 cells and suppresses the expression of collagen I/III, which has good potential for investigation in liver fibrosis. Benzyl-α-GalNAc also significantly enhances the anti-tumour activity of 5-FU (HY-90006) (e.g. pancreatic cancer) by inhibiting O-glycosylation.
  • HY-107420
    AY 9944
    		Inhibitor 99.71%
    AY 9944 is a specific cholesterol biosynthesis inhibitor. AY 9944 inhibits the 7-dehydro cholesterol Δ7-reductase (DHCR7) enzyme with an IC50 of 13 nM. AY 9944 causes hypocholesterolemia and accumulation of 7DHC. At high doses, AY 9944 inhibits also in cultured embryos sterol Δ7-Δ8 isomerase, which causes the accumulation of cholest-8-en-3β-ol.
  • HY-125006
    TRi-1
    		Inhibitor 99.91%
    TRi-1 is a potent, specific and irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy.
  • HY-107410
    SC-26196
    		Inhibitor 99.68%
    SC-26196 is a potent, orally active Delta6 desaturase (D6D, FADS2) inhibitor (IC50=0.2 μM in a rat liver microsomal assay). Antiinflammatory properties.
  • HY-16937
    ISA-2011B
    		Inhibitor 99.97%
    ISA-2011B is a PIP5K1α inhibitor with promising anticancer effects .
  • HY-148335
    IRG1-IN-1
    		Inhibitor 99.82%
    IRG1-IN-1 is an itaconic acid derivative. IRG1-IN-1 can inhibit immune-responsive gene 1 (IRG1) activity. IRG1-IN-1 can be used for the research of cancer, inflammation and autoimmune diseases.
  • HY-112134
    CSN5i-3
    		Inhibitor 99.95%
    CSN5i-3 is a potent, selective and orally available inhibitor of CSN5/Jab1, and inhibits CSN-catalysed Cul1 deneddylation with an IC50 value of 5.8 nM.
  • HY-103096
    R162
    		Inhibitor 99.98%
    R162 is a potent inhibitor of glutamate dehydrogenase 1 (GDH1/GLUD1), with anti-cancer properties.
  • HY-N0187
    4-Methylumbelliferone
    		Inhibitor 99.79%
    4-Methylumbelliferone is a hyaluronic acid biosynthesis inhibitor with antitumoral and antimetastatic effects.
  • HY-14667
    Lomitapide
    		Inhibitor 99.60%
    Lomitapide (AEGR-733; BMS-201038) is a potent inhibitor of microsomal triglyceride-transfer protein (MTP) with an IC50 of 8 nM in vitro.
  • HY-124861
    Malic enzyme inhibitor ME1
    		Inhibitor 99.53%
    Malic enzyme inhibitor ME1 (ME1; compound 1) is a potent inhibitor of Malic enzyme (ME1) with an IC50 of 0.15 μM.
  • HY-13541
    ADH-1
    		Inhibitor 99.93%
    ADH-1, an N-cadherin antagonist, inhibits N-cadherin mediated cell adhesion.
  • HY-11101
    Alendronate sodium hydrate
    		Inhibitor 99.6%
    Alendronate (sodium hydrate) is a farnesyl diphosphate synthase inhibitor with IC50 of 460 nM.
  • HY-112721
    FDI-6
    		Inhibitor 99.65%
    FDI-6 is an inhibitor of FOXM1. FDI-6 binds directly to FOXM1 protein, to displace FOXM1 from genomic targets in MCF-7 breast cancer cells, and induce concomitant transcriptional down-regulation.