2. Signaling Pathways
  3. GPCR/G Protein
  4. P2Y Receptor
  5. P2Y2 Receptor Isoform
  6. P2Y2 Receptor Agonist

P2Y2 Receptor Agonist

P2Y2 Receptor Agonists (6):

Cat. No. Product Name Effect Purity
  • HY-B0606
    Diquafosol tetrasodium
    		Agonist ≥99.0%
    Diquafosol tetrasodium is a P2Y2 receptor agonist that stimulates fluid and mucin secretion on the ocular surface, as a topical treatment of dry eye disease.
  • HY-154840
    4-Thiouridine 5′-triphosphate tetralithium
    		Agonist
    4-Thiouridine 5′-triphosphate (4-Thio-UTP) tetralithium is a potent P2Y2 and P2Y4 receptor agonist, with EC50s of 35 and 350 nM for hP2Y2 and hP2Y4, respectively. 4-Thiouridine 5′-triphosphate tetralithium can be used in the study of crosslinking experiments, labeling of transcriptional complex.
  • HY-108649A
    MRS2768 tetrasodium salt
    		Agonist 98.70%
    MRS2768 tetrasodium salt is a moderately potent and selective P2Y2 receptor agonist. MRS2768 tetrasodium salt has a protective effect on cardiomyocytes from ischemic damage in vivo and in vitro.
  • HY-116307
    2-Thio-UTP
    		Agonist
    2-Thio-UTP is a selective P2Y2 inhibitor with an EC50 value of 50 nM. 2-Thio-UTP reduces pro-fibrotic gene expression and protein α-smooth muscle actin. 2-Thio-UTP has the potential for the research of calcific aortic valve stenosis (CAVS) .
  • HY-B0606A
    Diquafosol
    		Agonist
    Diquafosol (INS365 free base) is a potent P2Y2 agonist. Diquafosol nhibits apoptosis and decreases ROS generation. Diquafosol has the potential for the research of dry eye.
  • HY-154840A
    4-Thiouridine 5′-triphosphate tetrasodium
    		Agonist
    4-Thiouridine 5′-triphosphate (4-Thio-UTP) tetrasodium is a potent P2Y2 and P2Y4 receptor agonist, with EC50s of 35 and 350 nM for hP2Y2 and hP2Y4, respectively. 4-Thiouridine 5′-triphosphate tetrasodium can be used in the study of crosslinking experiments, labeling of transcriptional complex.