1. Signaling Pathways
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N4106
    Dihydroartemisinic acid
    Inhibitor 99.58%
    Dihydroartemisinic acid (Dihydroqinghao acid) is a biosynthetic precursor to the antimalarial agent Artemisinin.
    Dihydroartemisinic acid
  • HY-N7227
    Anonaine
    Inhibitor
    Anonaine is an antiparasitic agent. Anonaine also is a glutathione S-transferase (GST) inhibitor.
    Anonaine
  • HY-136429A
    Ethylhydrocupreine hydrochloride
    Inhibitor 99.72%
    Ethylhydrocupreine hydrochloride (Optochin hydrochloride) is a quinine derivate with antimicrobial activity against S. pneumoniae. Ethylhydrocupreine hydrochloride also possesses antimalarial activity against Plasmodium falciparum, with an IC50 of 25.75 nM. Ethylhydrocupreine hydrochloride is a Gallus gallus taste 2 receptors (ggTas2r1, ggTas2r2 and ggTas2r7) agonist.
    Ethylhydrocupreine hydrochloride
  • HY-N3013
    Bruceine B
    Inhibitor 99.60%
    Bruceine B inhibits protein synthesis and nucleic acid synthesis.
    Bruceine B
  • HY-19285
    Sulfaclozine
    Inhibitor ≥99.0%
    Sulfaclozine (Sulfachloropyrazine) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis).
    Sulfaclozine
  • HY-B0497S1
    Niclosamide-13C6
    Inhibitor ≥99.0%
    Niclosamide-13C6 is the 13C6 labeled Niclosamide. Niclosamide (BAY2353) is an orally bioavailable chlorinated salicylanilide, with anthelmintic and potential antineoplastic activity. Niclosamide (BAY2353) inhibits STAT3 with IC50 of 0.25 μM in HeLa cells and inhibits DNA replication in a cell-free assay.
    Niclosamide-<sup>13</sup>C<sub>6</sub>
  • HY-118224
    BPH-715
    Inhibitor 99.62%
    BPH-715 is a bisphosphonate, inhibits Plasmodium liver-stage growth, with an IC50 of 10 μM for Plasmodium exoerythrocytic forms in HepG2 cells.
    BPH-715
  • HY-137445
    Modoflaner
    Inhibitor 98.01%
    Modoflaner is an isophenylamide insecticide. Modoflaner may act through allosteric regulation of gamma-aminobutyric acid-gated chloride channels.
    Modoflaner
  • HY-N5029
    Isofebrifugine
    Inhibitor 98.90%
    Isofebrifugine is a natural quinazolinone alkaloid with important physiological activities and good pharmacological effects. Antimalarial effect.
    Isofebrifugine
  • HY-135847
    Desmethyl ferroquine
    Inhibitor 98.02%
    Desmethyl ferroquine (SSR97213) is the active and major metabolite of Ferroquine. Ferroquine is an antimalarial. Desmethyl ferroquine shows significant activity against Chloroquine-susceptible and resistant P. falciparum strains.
    Desmethyl ferroquine
  • HY-N10096
    Epoxyazadiradione
    99.21%
    Epoxyazadiradione is a limonoid purified from neem (Azadirachta indica) fruits. Epoxyazadiradione inhibits the tautomerase activity of MIF of both human (huMIF) and malaria parasites (Plasmodium falciparum (PfMIF) and Plasmodium yoelii (PyMIF)) non-competitively in a reversible fashion (Ki, 2.11-5.23 μM). Epoxyazadiradione has the potential against proinflammatory reactions induced by MIF of both malaria parasites and human.
    Epoxyazadiradione
  • HY-12082A
    GSK369796 Dihydrochloride
    Inhibitor 99.56%
    GSK369796 Dihydrochloride is an affordable and effective antimalarial and inhibits hERG potassium ion channel repolarization with an IC50 of 7.5 μM.
    GSK369796 Dihydrochloride
  • HY-118383
    Agathisflavone
    Inhibitor 99.62%
    Agathisflavone is a flavonoid with antioxidant, anti-inflammatory, antiviral, antiparasitic, cytotoxic, neuroprotective, and hepatoprotective activities. Agathisflavone can improve tissue repair in a spinal cord injury model in rats.
    Agathisflavone
  • HY-N2377
    Allosecurinine
    Inhibitor 99.61%
    Allosecurinine (Phyllochrysine) is a Securinega alkaloid isolated from Phyllanthus glaucus .
    Allosecurinine
  • HY-120338
    RYL-552
    Inhibitor 98.63%
    RYL-552, a mitochondrial electron transport chain (ETC) inhibitor, is a P. falciparum NADH dehydrogenase 2 (PfNDH2) inhibtor.
    RYL-552
  • HY-66005R
    Acetaminophen (Standard)
    99.94%
    Acetaminophen (Standard) is the analytical standard of Acetaminophen. This product is intended for research and analytical applications. Acetaminophen (Paracetamol) is a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM; is a widely used antipyretic and analgesic agent. Acetaminophen is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
    Acetaminophen (Standard)
  • HY-147428
    Zolunicant
    Inhibitor 99.29%
    Zolunicant (MM-110) is a potent inhibitor against nicotinic α3β4 receptors with an IC50 of 0.90 μM to combat addiction. Zolunicant can decrease the self-administration of several addictive agents including morphine, methamphetamine, nicotine, and ethanol in rat model. Zolunicant can be studied as a potential research for multiple forms of agent abuse. Zolunicant also reveals a potent leishmanicide effect against Leishmania amazonensis.
    Zolunicant
  • HY-W054223
    N-Methyl lactam
    Inhibitor
    N-Methyl lactam (Compound 3b), a peramiue analogue, has feeding-deterrent activity against adult weevils.
    N-Methyl lactam
  • HY-A0130
    Sulfalene
    Inhibitor 99.73%
    Sulfalene (Sulfametopyrazine) is an antimalarial agent. Sulfalene is also a long-acting sulfonamide antibacterial.
    Sulfalene
  • HY-13833
    Endochin
    Inhibitor 99.41%
    Endochin is an antimalarial agent. Endochin inhibits T.gondii with an IC50 of 0.003 nM. Endochin is also active against experimental toxoplasmosis.
    Endochin

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