Antibiotic Inhibitor

Antibiotic Inhibitors (59):

Cat. No.	Product Name	Effect	Purity

HY-B1369

Imipenem monohydrate	Inhibitor	99.83%
Imipenem monohydrate, a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem monohydrate can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections.

HY-N6732

K-252a	Inhibitor	99.45%
K-252a, a staurosporine analog, inhibits protein kinase, with IC₅₀ values of 470 nM, 140 nM, 270 nM, and 1.7 nM for PKC, PKA, Ca²⁺/calmodulin-dependent kinase type II, and phosphorylase kinase, respectively. K-252a is a potent inhibitor (IC₅₀ of 3 nM) of the tyrosine protein kinase (TRK) activity of the NGF receptor gp140trk, the product of the trk protooncogene.

HY-B1369A

Imipenem	Inhibitor	99.83%
Imipenem (MK0787), a stable crystalline derivative of thienamycin, is an antibiotic and has the excellent activity against a broad range of gram-positive and gram-negative aerobic and anaerobic bacteria. Imipenem can be used for the research of carbapenem-nonsusceptible and P. aeruginosa biofilm infections.

HY-B1924

Norvancomycin hydrochloride	Inhibitor
Norvancomycin hydrochloride is suitable for endocarditis, osteomyelitis, pneumonia, sepsis or soft tissue infections caused by Staphylococcus aureus (including methicillin-resistant strains and multi-drug-resistant strains).

HY-105048

Omiganan	Inhibitor	99.15%
Omiganan is a cationic antimicrobial peptide. Omiganan as an analogue of indolicidin shows activity against gram-positive and gram-negative bacteria but also Candida spp. isolates. Omiganan can be used for the research of alcohol nose and acne.

HY-B1118

Secnidazole	Inhibitor	99.87%
Secnidazole (RP-14539) is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis.

HY-131150

Ristomycin sulfate	Inhibitor	≥99.0%
Ristomycin sulfate is a glycopeptide antibiotic isolated from Nocardia lurida.

HY-N7151

Aurachin D	Inhibitor	99.62%
Aurachin D is an antibiotic. Aurachin D inhibits Gram-positive bacteria and a few funguses. Aurachin D blocks NADH oxidation in beef heart submitochondrial particles.

HY-146331

PC190723	Inhibitor	98.34%
PC190723 (Compound 2) is an inhibitor of the bacterial cell division protein FtsZ with an IC₅₀ of 55 ng/ml. FtsZ-IN-3 exhibits anti-staphylococcal activity with MIC values of 1 µg/ml for MSSA and MRSA.

HY-N0113B

Hordenine hydrochloride	Inhibitor	99.82%
Hordenine (hydrochloride), an alkaloid found in plants, inhibits melanogenesis by suppression of cyclic adenosine monophosphate (cAMP) production.

HY-131146

AMOZ	Inhibitor
AMOZ, a tissue bound metabolite of Furaltadone, Furaltadone is a synthetic nitrofuran antibiotic widely used

HY-A0153

Cephapirin	Inhibitor
Cephapirin (Cefapirin) is an ephalosporin antibiotic with broad-spectrum antimicrobial activity.

HY-N10229

Harzianum A	Inhibitor
Harzianum A is a trichothecene that isolated from the soil-borne fungus Trichoderma harzianum. Harzianum A shows no cytotoxicity against baby hamster kidney cells, no activity against Gram-negative and Gram-positive bacteria, but modest antifungal activity at 100 μg/mL.

HY-B1118A

Secnidazole hemihydrate	Inhibitor
Secnidazole (RP-14539) hemihydrate is an orally active azole antibiotic and a imidazole mitigator of Serratia marcescens virulence. Secnidazole hemihydrate, as an analog of acylhomoserine lactones, effectively inhibits QS resulting in the attenuation of Pseudomonas aeruginosa pathogenesis. Secnidazole hemihydrate has antimicrobial activity against many anaerobic Gram-negative and Gram-positive bacterial species in vitro. Secnidazole hemihydrate can be used for the research of various diseases, such as amoebiasis and giardiasis, and bacterial vaginitis.

HY-W154333

H-Arg-OtBu dihydrochloride	Inhibitor
H-Arg-OtBu (dihydrochloride) is a membrane-targeting antimicrobial. H-Arg-OtBu (dihydrochloride) targets the negatively charged bacterial membrane via a combination of electrostatic and hydrophobic interactions. H-Arg-OtBu (dihydrochloride) can be used for bacterial infections diseases research.

HY-N0113BS

Hordenine-d₆ hydrochloride	Inhibitor
Hordenine-d₆ (Ordenina-d₆; Peyocactine-d₆) hydrochloride is deuterium-labeled Hordenine (hydrochloride) (HY-N0113B).

HY-P10700

RO7196472	Inhibitor
RO7196472 is a potent and selective macrocyclic peptide antibiotic that targets Acinetobacter strains. RO7196472 inhibits Acinetobacter strain activity by specifically binding to the Lipopolysaccharide (LPS) binding site on the LptB2FG complex located on the inner membrane of Acinetobacter strains, thereby blocking LPS transport and suppressing Acinetobacter strain activity.

HY-W008864

Lactose octaacetate	Inhibitor
Lactose octaacetate shows mild to moderate antifungal activity against some fungi, but it has low or no activity against bacteria and yeast. Lactose octaacetate shows low cytotoxicity to MDBK cells, Hep-2 and MDCK cells. Lactose octaacetate has antiviral activity against PV-1.

HY-124551

Viridiol	Inhibitor
Viridiol, a fungal metabolite from Trichodernza viride, shows antifungal activity.

HY-P3384

Pezadeftide	Inhibitor
Pezadeftide is a potent antifungal peptide. Pezadeftide can enter fungal cells and cause a rapid mitochondrial response that results in hyperpolarization of the mitochondrial membrane.

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