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  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (1328):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-122365R
    Inositol nicotinate (Standard)
    Inositol nicotinate (Standard) is the analytical standard of Inositol nicotinate. This product is intended for research and analytical applications. Inositol nicotinate, with vasodilatory effect, is used in the study of Peripheral arterial disease (PAD).
    Inositol nicotinate (Standard)
  • HY-B0917
    Bromindione
    		98.11%
    Bromindione is a potent and long-acting, Inandione-derived, oral anticoagulant compound.
    Bromindione
  • HY-105946A
    Hidrosmin (mixture)
    Hidrosmin (mixture) is a mixture of 3,5-di-O-(hydroxyethyl)diosmin and 3'-mono-O-(hydroxyethyl)diosmin.
    Hidrosmin (mixture)
  • HY-101595
    RPH-2823
    		≥99.0%
    RPH-2823, a basic triamterene derivative, induces a dose-dependent decrease in short-circuit current (SCC) and increase in transepithelial electrical resistance.
    RPH-2823
  • HY-B1136
    Menbutone
    		99.94%
    Menbutone (Genabilic acid), an oxobutyric acid derivative, is a choleretic. Menbutone can be used to treat digestive upsets (loss of appetite, indigestion, toxemia, or hepatic and pancreatic insufficiencies) in a variety of animal species, including different farm animals (cattle, sheep, goats, pigs), as well as in dogs.
    Menbutone
  • HY-U00153
    Dixyrazine
    		99.87%
    Dixyrazine, a phenothiazine derivative, can prevent brain oedema induced by intracarotid injection of protamine sulphate.
    Dixyrazine
  • HY-117109
    Amino Tadalafil
    		99.04%
    Amino Tadalafil is a structural analogue of Tadalafil (HY-90009A). Tadalafil is a potent inhibitor of PDE5 with applications in several conditions, including erectile dysfunction, pulmonary arterial hypertension, and lower urinary tract dysfunction.
    Amino Tadalafil
  • HY-76701
    4-Nitrothalidomide
    		99.53%
    4-Nitrothalidomide is a nitrosylated Thalidomide analogue. Thalidomide is a ligand for E3 ligase, which ubiquitinylates proteins, thus committing their fate to proteolytic destruction.
    4-Nitrothalidomide
  • HY-W004288
    Methyl myristate
    		99.70%
    Methyl myristate is a saturated fatty acid methyl ester obtained from the esterification of myristic acid. Methyl myristate shows a high melanin induction in B16F10 melanoma.
    Methyl myristate
  • HY-W004286
    Methyl laurate
    		99.49%
    Methyl laurate, a 12-carbon saturated fatty acid, is an esterified version of lauric acid.
    Methyl laurate
  • HY-Y1777
    2-Phenylacetophenone
    		99.96%
    2-Phenylacetophenone has broad-spectrum efflux pump inhibition activity. 2-Phenylacetophenone is a benzoin derivative used as a photoinitiator in vinyl polymerization.
    2-Phenylacetophenone
  • HY-145554
    Bafrekalant
    		99.67%
    Bafrekalant is a diazabicyclic substituted imidazo[l,2-a]pyrimidine-derivative. Bafrekalant has the potential for the research of breathing disorders, including sleep-related breathing disorders such as obstructive and central sleep apnea and snoring (extracted from patent WO2018228907A1).
    Bafrekalant
  • HY-B1714
    NSC 601980 analog
    		≥98.0%
    NSC 601980 analog is an analogue of NSC601980. In yeast screening experiments, NSC 601980 exhibited antitumor activity, effectively inhibiting cell proliferation in both COLO 205 and HT29 cell lines, with Log GI 50 values of -6.6 and -6.9, respectively.
    NSC 601980 analog
  • HY-N0572
    9-Hydroxycamptothecin
    		98.13%
    9-Hydroxycamptothecin (9-Hydroxycamptothecine; compound 23c) is a Camptothecin (HY-16560) derivative with anticancer activities.
    9-Hydroxycamptothecin
  • HY-136554
    WYC-210
    		99.18%
    WYC-210, a Tazarotene derivative, is a retinoid compound with lower anticancer activity. WYC-210 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    WYC-210
  • HY-121469
    Dioxone
    		≥98.0%
    Dioxone is a substance possessing convulsant properties qualitatively similar to leptazol and bemegride. Dioxone is orally active.
    Dioxone
  • HY-76779
    4-(Chloromethyl)-7-hydroxycoumarin
    4-(Chloromethyl)-7-hydroxycoumarin (compound 4) is a hydroxycoumarin derivative with potent antioxidant effect and high hydroxyl radical-scavenging property. 4-(Chloromethyl)-7-hydroxycoumarin contains a methyl group and a chlorine group in the heterocyclic ring. A series of coumarins incorporating hydroxy-, chloro- and/or chloromethyl-moieties has been investigated as potent inhibitors of the zinc enzyme carbonic anhydrase, expecially tumor-associated isoforms CA IX and XII.
    4-(Chloromethyl)-7-hydroxycoumarin
  • HY-N10478A
    Sitosterol sulfate (trimethylamine)
    		≥98.0%
    Sitosterol sulfate (trimethylamine) is an active compound. Sitosterol sulfate can be used in a variety of biological research.
    Sitosterol sulfate (trimethylamine)
  • HY-W197713
    2-Amino-N-phenylpropanamide hydrochloride
    		≥99.0%
    2-Amino-N-phenylpropanamide (Compound 5b) hydrochloride is a Tocainid (HY-B1798) analog. Tocainid is an antiarrythmic agent.
    2-Amino-N-phenylpropanamide hydrochloride
  • HY-B1185
    Beclamide
    		98.86%
    Beclamide is an active molecule with anticonvulsant activity, used as an anticonvulsant drug.
    Beclamide