1. Signaling Pathways
  2. Immunology/Inflammation
  3. IKZF Family
  4. IKZF Family Inhibitor

IKZF Family Inhibitor

IKZF Family Inhibitors (2):

Cat. No. Product Name Effect Purity
  • HY-145776
    ALV1
    Inhibitor
    ALV1 is a molecular glue degrader for Ikaros (IKZF1) and Helios (IKZF2), with DC50 values of 2.5 nM and 10.3 nM, respectively. ALV1 binds CRBN with an IC50 of 0.55 µM. ALV1 induces CRBN-Helios dimerization. ALV1 can be used to study the properties and functions of Treg cells.
  • HY-170518
    IKZF-IN-1
    Inhibitor
    IKZF-IN-1 (Compound I) is the molecular glue, that degrades ikaros zinc finger family (IKZF) IKZF 1/2/3/4, and can be used as an immunomodulator in research of cancer and viral infections.