2. Signaling Pathways
  3. Anti-infection
  4. TMV
  5. TMV Inhibitor

TMV Inhibitor

TMV Inhibitors (15):

Cat. No. Product Name Effect Purity
  • HY-162807
    TMV-IN-10
    		Inhibitor
    TMV-IN-10 (compound 4h) is an arecoline derivative with anti-tobacco mosaic virus (TMV) activity (EC50=146 µg/mL). TMV-IN-10 can be used in research on controlling crop pests and diseases and improving crop yields by acting on the viral coat protein (CP) to cause viral fragmentation.
  • HY-163999
    TMV-IN-12
    		Inhibitor
    TMV-IN-12 (compound 4) is an inhibitor of tobacco mosaic virus (TMV) with antifungal properties. TMV-IN-12 effectively prevents TMV particle aggregation and self-assembly of TMV capsid protein (TMV-CP) (Kd=0.142 μM), preventing TMV from infecting tobacco plants.
  • HY-W017463
    trans-3-(3-Pyridyl)acrylic acid
    		Inhibitor 99.31%
    trans-3-(3-Pyridyl)acrylic acid (compound 15) is a trans-3-aryl acrylic acid. trans-3-(3-Pyridyl)acrylic acid shows antiviral activity against tobacco mosaic virus (TMV).
  • HY-148569
    TMV-IN-3
    		Inhibitor
    TMV-IN-3, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-3 has antiviral activity against TMV with an EC50 value of 120.3 μg/mL. TMV-IN-3 can be used for the research of infection, inflammation and tumor.
  • HY-148568
    TMV-IN-2
    		Inhibitor
    TMV-IN-2, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-2 has antiviral activity against TMV with an EC50 value of 89.9 μg/mL. TMV-IN-2 can be used for the research of infection, inflammation and tumor.
  • HY-155045
    TMV-IN-6
    		Inhibitor
    TMV-IN-6 (Compound 4g) is a novel antiviral and fungicidal agent. TMV-IN-6 inhibits virus assembly by binding totobacco mosaic virus (TMV) CP and interfere with the assembly process of TMV CP and RNA.
  • HY-152259
    TMV-IN-4
    		Inhibitor
    TMV-IN-4 (compound 3) is a tobacco mosaic virus (TMV) inhibitor that effectively induces resistance and enhances plant tolerance to TMV infection by interacting with TMV helicase. TMV-IN-4 enhances peroxidase and superoxide dismutase activity, thereby increasing resistance to TMV in tobacco.
  • HY-N1836
    3-Acetonyl-3-hydroxyoxindole
    		Inhibitor
    3-Acetonyl-3-hydroxyoxindole (AHO) is a potent systemic acquired resistance (SAR) inducer in plants. 3-Acetonyl-3-hydroxyoxindole induces resistance in tobacco plants against infection with tobacco mosaic virus (TMV) and the fungal pathogen Erysiphe cichoracearum. 3-Acetonyl-3-hydroxyoxindole increases the level of pathogenesis-related gene 1 (PR-1) expression, salicylic acid (SA) accumulation and phenylalanine ammonia-lyase activity.
  • HY-163201
    TMV-IN-7
    		Inhibitor
    TMV-IN-7 (compound G2) is a potent inhibitor of tobacco mosaic virus (TMV). TMV-IN-7 exhibits strong hydrophobic interactions to obstructing the virus’s self-assembly.
  • HY-162400
    TMV-IN-8
    		Inhibitor
    TMV-IN-8 (compound 7 d) is an anti tobacco mosaic virus (TMV) agent with an antiviral EC50 of 157.6 μg/mL.TMV-IN-8 blocks the assembly of TMV by binding with coat protein (Kd = 0.7 μM) and suppressed TMV coat protein gene expression and biosynthesis process.
  • HY-148567
    TMV-IN-1
    		Inhibitor
    TMV-IN-1, chalcone derivative, is a tobacco mosaic virus (TMV) inhibitor. TMV-IN-1 has good therapeutic activity and protective activity against TMV with EC50 values of 70.7 μg/mL and 60.8 μg/mL, respectively. TMV-IN-1 can be used for the research of infection, inflammation and tumor.
  • HY-119458
    Luotonin A
    		Inhibitor
    Luotonin A is an antiviral and antiphytopathogenic fungus agent. Luotonin A has good antiviral activity against tobacco mosaic virus (TMV). Luotonin A also has certain inhibitory activity on topoisomerase I and topoisomerase II. Luotonin A shows antitumor activity.
  • HY-161955
    TMV-IN-11
    		Inhibitor
    TMV-IN-11 (compound syn-3g) is a potent TMV inhibitor with high inactivation capacity (IC50: 120.7 μg/mL). TMV-IN-11 can effectively inhibit the expression of TMV.
  • HY-169186
    TMV-IN-13
    		Inhibitor
    TMV-IN-13 (compund 5g) has anti-TMV activity.
  • HY-163754
    TMV-IN-9
    		Inhibitor
    TMV-IN-9 (compound A6) is an antiviral agent that displays excellent inactivating against tobacco mosaic virus (TMV) with an EC50 of 62.8 μg/mL. TMV-IN-9 shows strong binding capacity to TMV coat protein with a binding affinity value of 1.862 μM. TMV-IN-9 obviously destroys the integrity of the TMV particles and blocked the virus from infecting the host.