Tartaric acid disodium dihydrate (Synonyms: Sodium tartrate dibasic dihydrate; Sodium tartrate dihydrate)

Cat. No.: HY-D0850 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

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Tartaric acid disodium dehydrate (L-(+) -tartaric acid) is an orally active weak organic acid that can be isolated from grapes. Tartaric acid disodium dehydrate has vasodilatory and antihypertensive effects. Tartaric acid disodium dehydrate can be used as flavorings and antioxidants in a range of foods and beverages. Tartaric acid disodium dehydrate can be used in laser frequency doubling and optical limiting applications.

For research use only. We do not sell to patients.

Tartaric acid disodium dihydrate Chemical Structure

CAS No. : 6106-24-7

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	USD 44	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	USD 44	In-stock	Estimated Time of Arrival: December 31
Solid
5 g	USD 40	In-stock	Estimated Time of Arrival: December 31
10 g		Get quote
50 g		Get quote

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Other Forms of Tartaric acid disodium dihydrate:

Copper(II) tartrate hydrate Get quote
L-Tartaric acid diammonium Get quote
Potassium L-tartaric acid Get quote
L-Tartaric acid ammonium Get quote
L-Tartaric acid Get quote
L-Tartaric acid dipotassium hemihydrate Get quote
Rochelle salt Get quote
Tartaric acid disodium dihydrate (Standard) Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

IC₅₀ & Target

Microbial Metabolite

Human Endogenous Metabolite

In Vitro

L-Tartaric acid (1.66-6.64 mM) significantly reduces NEP and KCL-induced aortic ring vasoconstriction with EC₅₀ values of 4.119 mM and 4.00 mM, respectively^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

L-Tartaric acid (80-240 mg/kg; P.O.; Single dose) reduces blood pressure in hypertensive mice induced by L-NAME (60 mg/kg) ^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	Hypertensive Wistar rat model^[3]
Dosage:	80 mg/kg, 240 mg/kg
Administration:	Oral gavage (p.o.); Single dose. After L-NAME treatment (60.mg/kg; p.o.)
Result:	Reduced systolic blood pressure (SABP) and mild blood pressure (mid-BP) in rats at a dose of 240mg/kg, but had no effect on mean artery pressure, diastolic blood pressure, pulse pressure level, and heart rate.

Molecular Weight

232.10

Formula

C₄H₁₀Na₂O₈

CAS No.

6106-24-7

Appearance

Solid

Color

White to off-white

SMILES

OC([C@H](O)[C@@H](O)C(O)=O)=O.[2H2O].[2Na]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (430.85 mM; Need ultrasonic)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.3085 mL	21.5424 mL	43.0849 mL
5 mM	0.8617 mL	4.3085 mL	8.6170 mL
10 mM	0.4308 mL	2.1542 mL	4.3085 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 20 mg/mL (86.17 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (279 KB) SDS (393 KB)

COA (254 KB) HNMR (191 KB)

Handling Instructions (2659 KB)

References

[1]. Sasikala V, et al. Growth, molecular structure, NBO analysis and vibrational spectral analysis of l-tartaric acid single crystal. Spectrochim Acta A Mol Biomol Spectrosc. 2014 Apr 5;123:127-41. [Content Brief]

[2]. DeBolt S, et al. L-tartaric acid synthesis from vitamin C in higher plants. Proc Natl Acad Sci U S A. 2006 Apr 4;103(14):5608-13. [Content Brief]

[3]. Amssayef A, et al. L-Tartaric Acid Exhibits Antihypertensive and Vasorelaxant Effects: The Possible Role of eNOS/NO/cGMP Pathways. Cardiovasc Hematol Agents Med Chem. 2023;21(3):202-212. [Content Brief]

[4]. EFSA Panel on Food Additives and Flavourings (FAF); Younes M, et al. Re-evaluation of l(+)-tartaric acid (E 334), sodium tartrates (E 335), potassium tartrates (E 336), potassium sodium tartrate (E 337) and calcium tartrate (E 354) as food additives. EFSA J. 2020 Mar 11;18(3):e06030. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	4.3085 mL	21.5424 mL	43.0849 mL	107.7122 mL
	5 mM	0.8617 mL	4.3085 mL	8.6170 mL	21.5424 mL
	10 mM	0.4308 mL	2.1542 mL	4.3085 mL	10.7712 mL
	15 mM	0.2872 mL	1.4362 mL	2.8723 mL	7.1808 mL
	20 mM	0.2154 mL	1.0771 mL	2.1542 mL	5.3856 mL
	25 mM	0.1723 mL	0.8617 mL	1.7234 mL	4.3085 mL
	30 mM	0.1436 mL	0.7181 mL	1.4362 mL	3.5904 mL
	40 mM	0.1077 mL	0.5386 mL	1.0771 mL	2.6928 mL
	50 mM	0.0862 mL	0.4308 mL	0.8617 mL	2.1542 mL
	60 mM	0.0718 mL	0.3590 mL	0.7181 mL	1.7952 mL
	80 mM	0.0539 mL	0.2693 mL	0.5386 mL	1.3464 mL
	100 mM	0.0431 mL	0.2154 mL	0.4308 mL	1.0771 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Tartaric acid disodium dihydrate Related Classifications

Cardiovascular Disease

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tartaric acid disodium dihydrate6106-24-7Sodium tartrate dibasic dihydrate Sodium tartrate dihydratePhosphataseEndogenous Metabolitevasodilatationhypertensionfood additivesantioxidantcondimentlaser frequency doublingoptical limitingInhibitorinhibitorinhibit

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