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Tigloidin  (Synonyms: Tigloyl pseudotropine; Tiglylpseudotropine; Tiglyssin)

Cat. No.: HY-U00082 Purity: 99.91%
COA Handling Instructions

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Tigloidin is an analogue of atropine, with anticholinergic activity.

For research use only. We do not sell to patients.

Tigloidin Chemical Structure

Tigloidin Chemical Structure

CAS No. : 495-83-0

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Based on 1 publication(s) in Google Scholar

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Description

Tigloidin is an analogue of atropine, with anticholinergic activity.

In Vivo

Tigloidine hydrobromide (20-60 mg/kg, i.p.) fails to protect the mice against the lethal effect of physostigmine, but at 100 mg/kg and above, it protects 80% of the animals against the lethal effect. Tigloidine markedly prevents tremor and salivation produced by tremorine at 80-100 mg/kg, but fails to prevent these effects in doses up to 40 mg/kg. Tigloidine (up to 100 mg/kg, i.p) does not significantly affects reserpine and tetrabenazine induced sedation and ptosis in mice. Tigloidine (25-50 mg/kg, i.p.) also fails to cause any behavioral changes in the cats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

223.31

Formula

C13H21NO2
CAS No.
Appearance

Liquid (Density: 1.06±0.1 g/cm3)

Color

Light yellow to yellow

SMILES

C/C=C(C)/C(O[C@H]1C[C@@H](N2C)CC[C@@H]2C1)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 99.91%

COA (248 KB) HNMR (200 KB) LCMS (103 KB)

Handling Instructions (2659 KB)
References
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Tigloidin Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tigloidin495-83-0Tigloyl pseudotropine Tiglylpseudotropine TiglyssinOthersInhibitorinhibitorinhibit

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