2. Anti-infection
  3. Fungal
  4. Abafungin

Abafungin  (Synonyms: BAY-W-6341)

Cat. No.: HY-119847 Purity: 99.10%
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Abafungin, a antifungal agent, inhibitis the transmethylation at the C-24 position of the sterol side chain, catalyzed by the enzyme sterol-C-24-methyltransferase.

For research use only. We do not sell to patients.

Abafungin Chemical Structure

Abafungin Chemical Structure

CAS No. : 129639-79-8

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5 mg USD 80 In-stock
10 mg USD 135 In-stock
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Based on 1 publication(s) in Google Scholar

Abafungin Related Antibodies

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Description

Abafungin, a antifungal agent, inhibitis the transmethylation at the C-24 position of the sterol side chain, catalyzed by the enzyme sterol-C-24-methyltransferase.

Molecular Weight

378.49

Formula

C21H22N4OS
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC1=CC(C)=C(OC2=CC=CC=C2C3=CSC(NC4=NCCCN4)=N3)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (132.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6421 mL 13.2104 mL 26.4208 mL
5 mM 0.5284 mL 2.6421 mL 5.2842 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6421 mL 13.2104 mL 26.4208 mL 66.0519 mL
5 mM 0.5284 mL 2.6421 mL 5.2842 mL 13.2104 mL
10 mM 0.2642 mL 1.3210 mL 2.6421 mL 6.6052 mL
15 mM 0.1761 mL 0.8807 mL 1.7614 mL 4.4035 mL
20 mM 0.1321 mL 0.6605 mL 1.3210 mL 3.3026 mL
25 mM 0.1057 mL 0.5284 mL 1.0568 mL 2.6421 mL
30 mM 0.0881 mL 0.4403 mL 0.8807 mL 2.2017 mL
40 mM 0.0661 mL 0.3303 mL 0.6605 mL 1.6513 mL
50 mM 0.0528 mL 0.2642 mL 0.5284 mL 1.3210 mL
60 mM 0.0440 mL 0.2202 mL 0.4403 mL 1.1009 mL
80 mM 0.0330 mL 0.1651 mL 0.3303 mL 0.8256 mL
100 mM 0.0264 mL 0.1321 mL 0.2642 mL 0.6605 mL
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Abafungin Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Abafungin129639-79-8BAY-W-6341FungalInhibitorinhibitorinhibit

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