2. Protein Tyrosine Kinase/RTK
  3. Bcr-Abl
  4. Abl Cytosolic Substrate

Abl Cytosolic Substrate  (Synonyms: Abltide)

Cat. No.: HY-P1785 Purity: 99.60%
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Abl Cytosolic Substrate is a substrate for Abelson tyrosine kinase (Abl ). Abl Protein Tyrosine Kinase (AbI) is a truncated form of the v-AbI Protein Tyrosine Kinase, a partner in the Gag-Abl fusion protein of the Abelson murine leukemia virus.

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Custom Peptide Synthesis

Abl Cytosolic Substrate Chemical Structure

Abl Cytosolic Substrate Chemical Structure

CAS No. : 168202-46-8

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Based on 1 publication(s) in Google Scholar

Abl Cytosolic Substrate Related Antibodies

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Description

Abl Cytosolic Substrate is a substrate for Abelson tyrosine kinase (Abl ). Abl Protein Tyrosine Kinase (AbI) is a truncated form of the v-AbI Protein Tyrosine Kinase, a partner in the Gag-Abl fusion protein of the Abelson murine leukemia virus[1].

Molecular Weight

1336.58

Formula

C64H101N15O16
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Glu-Ala-Ile-Tyr-Ala-Ala-Pro-Phe-Ala-Lys-Lys-Lys
Sequence Shortening

EAIYAAPFAKKK
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (74.82 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.7482 mL 3.7409 mL 7.4818 mL
5 mM 0.1496 mL 0.7482 mL 1.4964 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

Animal weight
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g

Dosing volume
(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.7482 mL 3.7409 mL 7.4818 mL 18.7045 mL
5 mM 0.1496 mL 0.7482 mL 1.4964 mL 3.7409 mL
10 mM 0.0748 mL 0.3741 mL 0.7482 mL 1.8704 mL
15 mM 0.0499 mL 0.2494 mL 0.4988 mL 1.2470 mL
20 mM 0.0374 mL 0.1870 mL 0.3741 mL 0.9352 mL
25 mM 0.0299 mL 0.1496 mL 0.2993 mL 0.7482 mL
30 mM 0.0249 mL 0.1247 mL 0.2494 mL 0.6235 mL
40 mM 0.0187 mL 0.0935 mL 0.1870 mL 0.4676 mL
50 mM 0.0150 mL 0.0748 mL 0.1496 mL 0.3741 mL
60 mM 0.0125 mL 0.0623 mL 0.1247 mL 0.3117 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Abl Cytosolic Substrate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Abl Cytosolic Substrate168202-46-8AbltideBcr-AblInhibitorinhibitorinhibit

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