2. Peptides
  3. Peptide and Derivatives
  4. Inhibitors and Substrates
  5. Enzyme Substrates
  6. Ac-IEPD-AFC

Ac-IEPD-AFC is a substrate of Granzyme B.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Ac-IEPD-AFC Chemical Structure

Ac-IEPD-AFC Chemical Structure

CAS No. : 1135417-31-0

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5 mg USD 170 In-stock
10 mg USD 280 In-stock
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Based on 1 publication(s) in Google Scholar

Ac-IEPD-AFC Related Antibodies

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Description

Ac-IEPD-AFC is a substrate of Granzyme B[1].

In Vitro

The Km of human granzyme B for Ac-IEPD-AFC in granzyme B assay buffer is 585 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Ac-IEPD-AFC Related Antibodies
Molecular Weight

725.67

Formula

C32H38F3N5O11
CAS No.
Appearance

Solid

Color

White to off-white

Sequence Shortening

Ac-IEPD-AFC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture and light

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (137.80 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3780 mL 6.8902 mL 13.7804 mL
5 mM 0.2756 mL 1.3780 mL 2.7561 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3780 mL 6.8902 mL 13.7804 mL 34.4509 mL
5 mM 0.2756 mL 1.3780 mL 2.7561 mL 6.8902 mL
10 mM 0.1378 mL 0.6890 mL 1.3780 mL 3.4451 mL
15 mM 0.0919 mL 0.4593 mL 0.9187 mL 2.2967 mL
20 mM 0.0689 mL 0.3445 mL 0.6890 mL 1.7225 mL
25 mM 0.0551 mL 0.2756 mL 0.5512 mL 1.3780 mL
30 mM 0.0459 mL 0.2297 mL 0.4593 mL 1.1484 mL
40 mM 0.0345 mL 0.1723 mL 0.3445 mL 0.8613 mL
50 mM 0.0276 mL 0.1378 mL 0.2756 mL 0.6890 mL
60 mM 0.0230 mL 0.1148 mL 0.2297 mL 0.5742 mL
80 mM 0.0172 mL 0.0861 mL 0.1723 mL 0.4306 mL
100 mM 0.0138 mL 0.0689 mL 0.1378 mL 0.3445 mL
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Ac-IEPD-AFC Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Ac-IEPD-AFC1135417-31-0OthersInhibitorinhibitorinhibit

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