Adrenalone

Cat. No.: HY-B1308A: FAQs
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Adrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic. Adrenalone is an inhibitor of dopamine β oxidase. Adrenalone is chemically similar to known norepinephrine transporter (NET) ligands with an IC₅₀ of 36.9 μM.

For research use only. We do not sell to patients.

Adrenalone Chemical Structure

CAS No. : 99-45-6

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100 mg	USD 235	Ask For Quote & Lead Time

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Other In-stock Forms of Adrenalone:

Adrenalone hydrochloride

Other Forms of Adrenalone:

Adrenalone hydrochloride In-stock

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α adrenergic receptor β adrenergic receptor

Biological Activity
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Description	Adrenalone is an adrenergic agonist used as a topical vasoconstrictor and hemostatic. Adrenalone is an inhibitor of dopamine β oxidase. Adrenalone is chemically similar to known norepinephrine transporter (NET) ligands with an IC₅₀ of 36.9 μM^[1]^[2].
In Vitro	Adrenalone is a topical nasal decongestant, hemostatic, and vasoconstrictor, is a keton form of the natural substrate epinephrine^[1]. Adrenalone inhibits the activity of dopamine β-oxidase. Adrenalone inhibits substrate transport by NET^[2]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Adrenalone Related Antibodies
Molecular Weight	181.19
Formula	C₉H₁₁NO₃
CAS No.	99-45-6
SMILES	CNCC(C1=CC=C(O)C(O)=C1)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (266 KB) Handling Instructions (2659 KB)
References	[1]. M GOLDSTEIN,et al. Inhibition of dopamine beta oxidase by adrenalone. Nature.1961 Dec 16;192:1081. [Content Brief] [2]. Avner Schlessinger, et al. Structure-based discovery of prescription drugs that interact with the norepinephrine transporter, NET. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15810-5. [Content Brief]

Adrenalone Related Classifications

Endocrinology Cardiovascular Disease

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Adrenalone99-45-6Adrenergic ReceptorBeta ReceptorInflammasomePyroptosisInflammationPotassiumTyrosinekinaseSykSrcGPVIsignalingPARPiceatannolInhibitorinhibitorinhibit

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