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ALKBH1-IN-2 (Compound 16) is a derivative of ALKBH1-IN-1 (HY-163385). ALKBH1-IN-2 is an ALKBH1 inhibitor. ALKBH1-IN-2 can modulate the 6mA levels.

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ALKBH1-IN-2 Chemical Structure

ALKBH1-IN-2 Chemical Structure

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5 mg USD 125 In-stock
10 mg USD 200 In-stock
25 mg USD 400 In-stock
50 mg USD 640 In-stock
100 mg USD 980 In-stock
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Based on 1 publication(s) in Google Scholar

ALKBH1-IN-2 Related Antibodies

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Description

ALKBH1-IN-2 (Compound 16) is a derivative of ALKBH1-IN-1 (HY-163385). ALKBH1-IN-2 is an ALKBH1 inhibitor. ALKBH1-IN-2 can modulate the 6mA levels[1].

IC50 & Target

ALKBH1[1]
Molecular Weight

395.29

Formula

C16H12F3N5O4
Appearance

Solid

Color

White to off-white

SMILES

O=C(NO)C1=CN(N=C1)C2=NC=C(C=N2)OCC3=CC=CC(OC(F)(F)F)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 12.5 mg/mL (31.62 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5298 mL 12.6489 mL 25.2979 mL
5 mM 0.5060 mL 2.5298 mL 5.0596 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5298 mL 12.6489 mL 25.2979 mL 63.2447 mL
5 mM 0.5060 mL 2.5298 mL 5.0596 mL 12.6489 mL
10 mM 0.2530 mL 1.2649 mL 2.5298 mL 6.3245 mL
15 mM 0.1687 mL 0.8433 mL 1.6865 mL 4.2163 mL
20 mM 0.1265 mL 0.6324 mL 1.2649 mL 3.1622 mL
25 mM 0.1012 mL 0.5060 mL 1.0119 mL 2.5298 mL
30 mM 0.0843 mL 0.4216 mL 0.8433 mL 2.1082 mL
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ALKBH1-IN-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ALKBH1-IN-2Others6mAderivativeInhibitorinhibitorinhibit

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