1. Neuronal Signaling GPCR/G Protein Immunology/Inflammation Membrane Transporter/Ion Channel Protein Tyrosine Kinase/RTK
  2. Serotonin Transporter 5-HT Receptor Histamine Receptor mAChR Adrenergic Receptor Sodium Channel Trk Receptor
  3. Amitriptyline hydrochloride (Standard)

Amitriptyline hydrochloride (Standard) 

Cat. No.: HY-B0527AR Purity: 99.03%
SDS COA Handling Instructions

Amitriptyline (hydrochloride) (Standard) is the analytical standard of Amitriptyline (hydrochloride). This product is intended for research and analytical applications. Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET), with Kis of 3.45 nM and 13.3 nM for human SERT and NET, respectively. Amitriptyline hydrochloride also weakly binds to dopamine reuptake transporter (DAT) with a Ki of 2.58 μM. Amitriptyline hydrochloride also inhibits adrenergic, muscarinic, histamine and 5-HT receptors. Amitriptyline hydrochloride is a TrkA and TrkB receptors agonist with potent neurotrophic activity. Amitriptyline hydrochloride has antidepressant activity.

For research use only. We do not sell to patients.

Amitriptyline hydrochloride (Standard) Chemical Structure

Amitriptyline hydrochloride (Standard) Chemical Structure

CAS No. : 549-18-8

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10 mg USD 52 In-stock
25 mg USD 104 In-stock
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100 mg USD 234 In-stock
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Description
Molecular Weight

313.86

Formula

C₂₀H₂₄ClN

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CN(C)CC/C=C1C2=CC=CC=C2CCC3=C\1C=CC=C3.Cl

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Amitriptyline hydrochloride (Standard)
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HY-B0527AR
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