2. GPCR/G Protein Neuronal Signaling
  3. mAChR
  4. Anisotropine bromide

Anisotropine bromide  (Synonyms: Octatropine bromide)

Cat. No.: HY-B1475 Purity: ≥98.0%
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Anisotropine (Octatropine) bromide is an orally active anticholinergic muscarinic antagonist. Anisotropine bromide can inhibit gastric acid secretion and is used as an adjunct to peptic ulcers.

For research use only. We do not sell to patients.

Anisotropine bromide Chemical Structure

Anisotropine bromide Chemical Structure

CAS No. : 80-50-2

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Based on 1 publication(s) in Google Scholar

Anisotropine bromide Related Antibodies

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Description

Anisotropine (Octatropine) bromide is an orally active anticholinergic muscarinic antagonist. Anisotropine bromide can inhibit gastric acid secretion and is used as an adjunct to peptic ulcers[1].

In Vivo

Anisotropine bromide (intravenous injection, 0.5 μM and 0.1 mL, once) can block acetylcholine-induced vocalization, intestinal spasm and intestinal contractions in conscious or anesthetized dogs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Dogs weighing 2.5 to 5.0 kg[1]
Dosage: 0.5 μM, 0.1 mL
Administration: Intravenous injection; once
Result: Inhibited the acetylcholine-induced vocalization with maximum inhibition of 85.1% and the acetylcholine-induced intestinal spasm with maximum inhibition of 79%.
Molecular Weight

362.35

Formula

C17H32BrNO2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[N+]1([C@H]2C[C@@H](C[C@@H]1CC2)OC(C(CCC)CCC)=O)C.[Br-]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (137.99 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7598 mL 13.7988 mL 27.5976 mL
5 mM 0.5520 mL 2.7598 mL 5.5195 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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(per animal)

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.7598 mL 13.7988 mL 27.5976 mL 68.9941 mL
5 mM 0.5520 mL 2.7598 mL 5.5195 mL 13.7988 mL
10 mM 0.2760 mL 1.3799 mL 2.7598 mL 6.8994 mL
15 mM 0.1840 mL 0.9199 mL 1.8398 mL 4.5996 mL
20 mM 0.1380 mL 0.6899 mL 1.3799 mL 3.4497 mL
25 mM 0.1104 mL 0.5520 mL 1.1039 mL 2.7598 mL
30 mM 0.0920 mL 0.4600 mL 0.9199 mL 2.2998 mL
40 mM 0.0690 mL 0.3450 mL 0.6899 mL 1.7249 mL
50 mM 0.0552 mL 0.2760 mL 0.5520 mL 1.3799 mL
60 mM 0.0460 mL 0.2300 mL 0.4600 mL 1.1499 mL
80 mM 0.0345 mL 0.1725 mL 0.3450 mL 0.8624 mL
100 mM 0.0276 mL 0.1380 mL 0.2760 mL 0.6899 mL
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Anisotropine bromide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Anisotropine80-50-2OctatropinemAChRMuscarinic acetylcholine receptoranticholinergicmuscarinicgastric acidpeptic ulcersInhibitorinhibitorinhibit

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