Phospho-PKR (Thr451) Antibody (YA1025)

Cat. No.: HY-P81299: FAQs
Data Sheet User Guide for Antibodies

Phospho-PKR (Thr451) Antibody (YA1025) is a biotin-conjugated non-conjugated IgG antibody, targeting Phospho-PKR (Thr451), with a predicted molecular weight of 62 kDa (observed band size: 74 kDa). Phospho-PKR (Thr451) Antibody (YA1025) can be used for WB experiment in human background.

For research use only. We do not sell to patients.

Size	Price	Stock
10 μL	$70	Ask For Quote & Lead Time
50 μL	$185	Ask For Quote & Lead Time
100 μL	$300	Ask For Quote & Lead Time

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Biological Activity
Technical Parameters
Properties
Documentation

Description	Phospho-PKR (Thr451) Antibody (YA1025) is a biotin-conjugated non-conjugated IgG antibody, targeting Phospho-PKR (Thr451), with a predicted molecular weight of 62 kDa (observed band size: 74 kDa). Phospho-PKR (Thr451) Antibody (YA1025) can be used for WB experiment in human background.
Background	The protein encoded by The related gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. The protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses.
Gene ID	5610
Synonyms	EIF2AK2; PKR; PRKR; Interferon-induced; double-stranded RNA-activated protein kinase; Eukaryotic translation initiation factor 2-alpha kinase 2; eIF-2A protein kinase 2; Interferon-inducible RNA-dependent protein kinase; P1/eIF-2A protein k
Molecular Weight	Predicted band size: 62 kDa; Observed band size: 74 kDa
Purity	Affinity Purified
Conjugation	Non-conjugated
Modification	Phosphorylated
Research Field	Signal Transduction
Product Categories	Primary Antibody; Recombinant Rabbit Monoclonal Antibody
Clonality	Recombinant, Monoclonal
Host	Rabbit
Reactivity	Human
SwissProt ID	P19525
Dilution Ratio	WB: 1/500-1/1000
Application	WB
Appearance	Liquid
Formulation	Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability	Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping	Shipping with blue ice.
Isotype	IgG
Sensitivity	Endogenous
Immunogen	A synthetic phosphopeptide corresponding to residues surrounding Thr451 of human PKR
Documentation	Data Sheet (232 KB) User Guide for Antibodies (1077 KB)

Phospho-PKR (Thr451) Antibody (YA1025) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Phospho-PKR (Thr451) Antibody (YA1025)

Biological Activity

Technical Parameters

Properties

Documentation

Phospho-PKR (Thr451) Antibody (YA1025) Related Classifications

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