EIF2AK2 - eukaryotic translation initiation factor 2 alpha kinase 2 Gene

Homo sapiens

Also known as PKR; PRKR; DYT33; LEUDEN; EIF2AK1; PPP1R83

Gene ID: 5610 | Gene type: protein coding

About EIF2AK2

Cytogenetic location: 2p22.2 Genomic coordinates (GRCh38): 2:37,099,210-37,156,980 (from NCBI)

This gene has 14 transcripts (splice variants), 153 orthologues, 8 paralogues and is associated with 4 phenotypes. Ubiquitous expression in bone marrow (RPKM 8.7), brain (RPKM 6.4) and 25 other tissues.

Summary

The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. The encoded protein plays an important role in the innate immune response against multiple DNA and RNA viruses. [provided by RefSeq, Jul 2021]

EIF2AK2 Products(3)

mRNA	Protein	Name
NM_001135651.3	NP_001129123.1	interferon-induced, double-stranded RNA-activated protein kinase isoform a
NM_001135652.2	NP_001129124.1	interferon-induced, double-stranded RNA-activated protein kinase isoform b
NM_002759.4	NP_002750.1	interferon-induced, double-stranded RNA-activated protein kinase isoform a

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables double-stranded RNA binding	IDA IDA: Inferred from direct assay	21266579	GOA
enables eukaryotic translation initiation factor 2alpha kinase activity	IMP IMP: Inferred from mutant phenotype	25329545	GOA
enables identical protein binding	IPI IPI: Inferred from physical interaction	16373505	GOA
enables kinase activity	IDA IDA: Inferred from direct assay	21123651	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	8576172	GOA
enables protein kinase activity	IDA IDA: Inferred from direct assay	12882984	GOA
enables protein kinase activity	IMP IMP: Inferred from mutant phenotype	21123651	GOA

Biological Process GO Annotation	Evidence	Reference	Source
involved in antiviral innate immune response	IDA IDA: Inferred from direct assay	22948139	GOA
involved in cellular response to amino acid starvation	IMP IMP: Inferred from mutant phenotype	25329545	GOA
involved in defense response to virus	IEP IEP: Inferred from expression pattern	32634389	GOA
involved in negative regulation of osteoblast proliferation	IMP IMP: Inferred from mutant phenotype	16216244	GOA
involved in negative regulation of translation	IDA IDA: Inferred from direct assay	12882984	GOA
involved in negative regulation of translation	IMP IMP: Inferred from mutant phenotype	12610133	GOA
involved in negative regulation of viral genome replication	IMP IMP: Inferred from mutant phenotype	19189853	GOA
involved in positive regulation of MAPK cascade	IMP IMP: Inferred from mutant phenotype	15229216	GOA
involved in positive regulation of NF-kappaB transcription factor activity	IDA IDA: Inferred from direct assay	15121867	GOA
involved in protein autophosphorylation	IDA IDA: Inferred from direct assay	22801494	GOA
involved in protein autophosphorylation	IMP IMP: Inferred from mutant phenotype	16216244	GOA
involved in protein phosphorylation	IDA IDA: Inferred from direct assay	19189853	GOA
involved in response to interferon-alpha	IDA IDA: Inferred from direct assay	19840259	GOA
involved in response to virus	IMP IMP: Inferred from mutant phenotype	19189853	GOA

Cellular Component GO Annotation	Evidence	Reference	Source
is active in cytoplasm	IDA IDA: Inferred from direct assay	21123651	GOA
located in cytoplasm	IDA IDA: Inferred from direct assay	15121867	GOA
located in perinuclear region of cytoplasm	IDA IDA: Inferred from direct assay	15121867	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

EIF2AK2 Protein Structure

dsrm

Pkinase

0
100
200
300
400
500
551 a.a.

Protein Preferred Names

Protein Names

interferon-induced, double-stranded RNA-activated protein kinase

P1/eIF-2A protein kinase

EIF2AK2 Protein-protein interaction Information

Type Cross Intra	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	Reference
Intra	EIF2AK2	P19525	EDC4	Homo sapiens	Q6P2E9	Anti Tag CoIP	21903422
Intra	EIF2AK2	P19525	MOV10	Homo sapiens	Q9HCE1	Anti Tag CoIP	21903422
Intra	EIF2AK2	P19525	MOV10	Homo sapiens	Q9HCE1	Pull Down	32707033
Intra	EIF2AK2	P19525	EIF2S1	Homo sapiens	P05198	Competition Binding	9431994
Intra	EIF2AK2	P19525	EIF2S1	Homo sapiens	P05198	Anti Bait CoIP	9431994
Intra	EIF2AK2	P19525	EIF2S1	Homo sapiens	P05198	Protein Kinase Assay	18971339
Intra	EIF2AK2	P19525	EIF2S1	Homo sapiens	P05198	Protein Kinase Assay	9431994
Intra	EIF2AK2	P19525	ADARB1	Homo sapiens	P78563-4	Validated Y2H	32296183
Intra	EIF2AK2	P19525	DHX30	Homo sapiens	Q7L2E3	Pull Down	32707033
Intra	EIF2AK2	P19525	DHX30	Homo sapiens	Q7L2E3	TAP	23455922
Intra	EIF2AK2	P19525	DHX30	Homo sapiens	Q7L2E3	Anti Tag CoIP	21903422
Intra	EIF2AK2	P19525	PRKRA	Homo sapiens	O75569-1	NMR	16785445
Intra	EIF2AK2	P19525	PRKRA	Homo sapiens	O75569-1	Pull Down	16785445
Intra	EIF2AK2	P19525	ZNF346	Homo sapiens	Q9UL40	Pull Down	32707033
Intra	EIF2AK2	P19525	ZNF346	Homo sapiens	Q9UL40	Anti Tag CoIP	21903422
Intra	EIF2AK2	P19525	ZNF346	Homo sapiens	Q9UL40	Anti Tag CoIP	35271311
Intra	EIF2AK2	P19525	N	SARS-CoV-2	P0DTC9	Anti Tag CoIP	34035218
Intra	EIF2AK2	P19525	DHX9	Homo sapiens	Q08211	Anti Tag CoIP	35271311
Intra	EIF2AK2	P19525	DHX9	Homo sapiens	Q08211	Anti Bait CoIP	21903422
Intra	EIF2AK2	P19525	DHX9	Homo sapiens	Q08211	Anti Tag CoIP	21903422
Intra	EIF2AK2	P19525	EIF6	Homo sapiens	P56537	Anti Tag CoIP	21903422
Intra	EIF2AK2	P19525	DICER1	Homo sapiens	Q9UPY3	Anti Tag CoIP	21903422
Intra	EIF2AK2	P19525	CDK1	Homo sapiens	P06493	Protein Kinase Assay	20395957
Intra	EIF2AK2	P19525	NLRP3	Homo sapiens	Q96P20	Anti Bait CoIP	22801494
Intra	EIF2AK2	P19525	NLRP3	Homo sapiens	Q96P20	Anti Tag CoIP	22801494
Intra	EIF2AK2	P19525	PRKRA	Homo sapiens	O75569	TAP	23455922
Intra	EIF2AK2	P19525	PRKRA	Homo sapiens	O75569	Pull Down	32707033
Intra	EIF2AK2	P19525	PRKRA	Homo sapiens	O75569	Anti Tag CoIP	21903422
Intra	EIF2AK2	P19525	STAU2	Homo sapiens	Q9NUL3	Pull Down	32707033
Intra	EIF2AK2	P19525	STAU2	Homo sapiens	Q9NUL3	Anti Tag CoIP	21903422
Intra	EIF2AK2	P19525	FTSJ3	Homo sapiens	Q8IY81	Anti Tag CoIP	21903422
Intra	EIF2AK2	P19525	FTSJ3	Homo sapiens	Q8IY81	Pull Down	32707033
Intra	EIF2AK2	P19525	TOLLIP	Homo sapiens	Q9H0E2	Anti Tag CoIP	21903422
Intra	EIF2AK2	P19525	NPM1	Homo sapiens	P06748	Anti Bait CoIP	16957780
Intra	EIF2AK2	P19525	NPM1	Homo sapiens	P06748	Imaging	16957780
Cross	EIF2AK2	P19525	vIRF-2	Human herpesvirus 8	Q2HR71	Pull Down	11160738
Intra	EIF2AK2	P19525	TARBP2	Homo sapiens	Q15633	Anti Tag CoIP	21903422
Cross	EIF2AK2	P19525	US11	Human herpesvirus 1	P04487	Protein Kinase Assay	11836380
Cross	EIF2AK2	P19525	US11	Human herpesvirus 1	P04487	Anti Bait CoIP	11836380
Cross	EIF2AK2	P19525	DNAJC3	Bos taurus	Q27968	Pull Down	8576172
Cross	EIF2AK2	P19525	P27958-PRO_0000037570	Hepatitis C virus	P27958-PRO_0000037570	Anti Tag CoIP	12610133
Cross	EIF2AK2	P19525	P27958-PRO_0000037570	Hepatitis C virus	P27958-PRO_0000037570	IF	10390359
Cross	EIF2AK2	P19525	P27958-PRO_0000037570	Hepatitis C virus	P27958-PRO_0000037570	Pull Down	10390359
Cross	EIF2AK2	P19525	OPG041	Vaccinia virus	P20639	SPR	18971339
Cross	EIF2AK2	P19525	OPG041	Vaccinia virus	P20639	Competition Binding	9431994
Cross	EIF2AK2	P19525	P27958-PRO_0000037576	Hepatitis C virus	P27958-PRO_0000037576	Protein Kinase Assay	9143277
Cross	EIF2AK2	P19525	P27958-PRO_0000037576	Hepatitis C virus	P27958-PRO_0000037576	Y2H	9143277
Cross	EIF2AK2	P19525	P27958-PRO_0000037576	Hepatitis C virus	P27958-PRO_0000037576	Pull Down	9143277

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant EIF2AK2 Proteins

Cat. No.	Product Name	Accession	Purity
HY-P700582	EIF2AK2 Protein, Human (P. pastoris, His)	P19525 (A2-C551)	≥95%

Related Diseases

Diseases

Alias

Dystonia 33

DYT33

Leukoencephalopathy, Developmental Delay, And Episodic Neurologic Regression Syndrome

LEUDEN

Leuden Syndrome

Early-Onset Generalized Limb-Onset Dystonia

Dystonia Musculorum Deformans	Eotd
Early-Onset Generalized Torsion Dystonia	Early-Onset Isolated Dystonia
Early-Onset Primary Dystonia	Early-Onset Torsion Dystonia
Idiopathic Torsion Dystonia	Oppenheim Dystonia
Dystonia 1, Torsion, Autosomal Dominant	Early Onset Torsion Dystonia
Dystonia 3, Torsion, X-Linked

Hepatitis C

Chronic Hepatitis C	Hepatitis C Infection
Hepatitis Nona Nonb	Nanbh
Viral Hepatitis C	Hepatitis C Chronic
Hepatitis C, Chronic	Chronic Type C Viral Hepatitis
Chronic Hcv - [Hepatitis C Virus] Infection	Hepatitis C Nos
Hepatitis C Infection Nos	Hepatitis C-Related Cirrhosis
Type C Viral Hepatitis	Hep C Nos

Vaccinia

Herpes Simplex

Herpes Simplex Infections	Herpesvirus Hominis Disease
Herpes Simplex Disease	Herpesviral Infection Due To Herpes Simplex
Infections Due To Simplex Virus	Herpes Nos

Hepatitis C Virus

Hepatitis C Virus, Susceptibility To	Hepatitis C Virus Infection, Response To Therapy Of
Hcv	Hcv, Susceptibility To
Hepatitis C Virus, Resistance To	Hepatitis C Virus, Response To Therapy Of
Resistance To Hepatitis C Virus

Measles

Rubeola	Morbilli
Measles Nos	Koplik Spots

Rift Valley Fever

Rfv - [Rift Valley Fever]

Chronic Fatigue Syndrome

Myalgic Encephalomyelitis	Postviral Fatigue Syndrome
Cfs	Myalgic Encephalitis
Encephalomyelitis, Myalgic	Chronic Fatigue
Fatigue Syndrome, Chronic	Benign Myalgic Encephalomyelitis
Akureyri	Akureyri Disease
Cfs - [Chronic Fatigue Syndrome]	Epidemic Neuromyasthenia
Myalgic Encephalomyelitis Syndrome	Me - [Myalgic Encephalomyelitis]
Pvfs - [Postviral Fatigue Syndrome]	Neuromyasthenia
Iceland Disease	Icelandic Disease

Hepatitis

Chronic Hepatitis	Chronic Persistent Hepatitis
Acute Hepatitis	Hepatitis, Chronic
Acute And Subacute Liver Necrosis	Acute/Subac. Necrosis Of Liver
Animal Hepatitis	Hepatitis Chronic
Hepatitis A	Hepatitis, Animal
Hepatitis Due To Toxoplasmosis	Hepatitis In Toxoplasmosis
Toxoplasmal Hepatitis	Chronic Hepatitis, Unspecified
Chronic Active Hepatitis Nec	Other Specified Chronic Hepatitis
Chronic Persistent Hepatitis Nec	Chronic Lobular Hepatitis Nec

Influenza

Flu	Influenza With Non-Respiratory Manifestation
Influenza With Other Manifestations	Influenza, Human
Influenza, Susceptibility To	Seasonal Influenza, Virus Identified

Hepatitis D

Delta Hepatitis	Hepatitis Delta
Hdv	Hepatitis D Virus
Hepatitis D Infection

Mumps

Parotitis Due To Mumps Virus	Mumps Nos
Epidemic Parotitis	Infectious Parotitis

Creutzfeldt-Jakob Disease

Variant Creutzfeldt-Jakob Disease	CJD
Bovine Spongiform Encephalopathy	Vcjd
Inherited Creutzfeldt-Jakob Disease	Creutzfeldt-Jakob Disease, Familial
Creutzfeldt Jakob Disease	Creutzfeldt-Jacob Disease
Creutzfeldt Jacob Disease	Sporadic Creutzfeldt-Jakob Disease
Encephalopathy, Bovine Spongiform	Creutzfeldt-Jakob Disease, Variant, Resistance To
Creutzfeldt-Jakob Disease, Variant	Creutzfeldt Jacob Syndrome
Jakob-Creutzfeldt Disease	Subacute Spongiform Encephalopathy
Transmissible Virus Dementia	New Variant Of Cjd
Nv-Cjd	Variant Cjd
Variant Creutzfeldt-Jacob Disease	Sporadic Cjd
Inherited Cjd	Acquired Creutzfeldt-Jakob Disease
Variant Mcj	Encephalopathy Bovine Spongiform
Familial Creutzfeldt-Jakob Disease	Creutzfeldt-Jakob Syndrome
New Variant Creutzfeldt-Jakob Disease	Creutzfeldt-Jakob Disease, Sporadic
Acquired Cjd	Scjd - [Sporadic Creutzfeldt-Jakob Disease]
Idiopathic Creutzfeldt-Jakob Disease	Creutzfeld-Jakob Disease Nos
Vcjd - [Variant Creutzfeldt-Jakob Disease]

Stomatitis

Acute Leukemia

Stem Cell Leukaemia	Stem Cell Leukemia
Acute Leukemias	Acute Undifferentiated Leukemia
Undifferentiated Leukemia	Acute Leukaemia Of Unspecified Cell Type Without Mention Of Remission
Blast Cell Leukaemia	Blast Leukaemia
Blastic Leukaemia	Undifferentiated Leukaemia

Viral Infectious Disease

Viral Disease	Arbovirus Infections
Virus Infection	Virus Diseases
Viral Infection	Viral Infections
Virus Infections

Newcastle Disease

Newcastle'S Disease

Pseudo-Fowlpest

Hepatitis B

Chronic Hepatitis B	Hepatitis B Infection
Serum Hepatitis	HBV
Hepatitis B Chronic	Hbv, Susceptibility To
Hepatitis B, Chronic	Chronic Hepatitis B Without Delta Agent
Chronic Hbv - [Hepatitis B Virus] Infection	Hepatitis B Nos
Chronic Type B Viral Hepatitis	Hep B Nos

Fanconi Anemia, Complementation Group C

Fanconi Anemia Complementation Group C	FANCC
Facc	Fac
Fa3	Fanconi Pancytopenia Type 3
Fanconi Pancytopenia, Type 3	Faces Syndrome
Facial Features , Anorexia, Cachexia, Eye And Skin Anomalies	Friedman-Goodman Syndrome
Abnormality Of The Face

Dystonia

Dystonic Disease	Dystonic Disorder
Dystonia Disorders	Neuroleptic Dyskinesia

Melanoma

Malignant Melanoma	Cutaneous Melanoma
Naevocarcinoma	Malignant Melanomas

Microphthalmia With Limb Anomalies

Waardenburg Anophthalmia Syndrome	Ophthalmoacromelic Syndrome
OAS	MLA
Anophthalmia-Syndactyly	Anophthalmia-Syndactyly Syndrome
Anophthalmos With Limb Anomalies	Anophthalmia Waardenburg Syndrome
Anophthalmos-Syndactyly	Ophthalmo-Acromelic Syndrome
Anophthalmia-Waardenburg Syndrome	Anophthalmos-Limb Anomalies Syndrome
Syndactyly-Anophthalmos Syndrome	Microphthalmia, With Limb Anomalies

Lung Cancer

Lung Carcinoma	Non-Small Cell Lung Carcinoma
Lung Cancer, Susceptibility To	Lung Cancer, Protection Against
Adenocarcinoma Of Lung, Somatic	Adenocarcinoma Of Lung, Response To Tyrosine Kinase Inhibitor In
Nonsmall Cell Lung Cancer	Lung Neoplasm
Carcinoma Of Lung	Lung Non-Small Cell Carcinoma
Non-Small Cell Lung Cancer	Nsclc
Lung Neoplasms	Malignant Neoplasm Of Lung
Alveolar Cell Carcinoma	Nonsmall Cell Lung Cancer, Somatic
Nonsmall Cell Lung Cancer, Response To Tyrosine Kinase Inhibitor In	Nonsmall Cell Lung Cancer, Susceptibility To
Lung Cancer, Somatic	Lung Cancer, Resistance To
Cancer Of Lung	Cancer Of Bronchus
Cancer Of The Lung	Lung Malignancies
Lung Malignant Tumors	Malignant Lung Tumor
Malignant Tumor Of Lung	Pulmonary Cancer
Pulmonary Carcinoma	Pulmonary Neoplasms
Respiratory Carcinoma	LNCR
Adenocarcinoma Of Lung	Neoplasm Of Lung
Cancer Lung	Carcinoma Non-Small Cell Lung
Carcinoma, Non-Small-Cell Lung	Lung Cancers
Lung Carcinomas	Cancer, Lung
Cancer, Lung, Non-Small Cell	Primary Malignant Neoplasm Of Lung
Bronchioloalveolar Adenocarcinoma

Immune Deficiency Disease

Immunodeficiency	Primary Immunodeficiency
Primary Immunodeficiency Disease	Immunologic Deficiency Syndromes
Hypoimmunity	Immune Deficiency Disorder
Immunodeficiency Syndrome	Immune Disorder
Primary Immune Deficiency Disorder	Immune System Diseases
Human Immunodeficiency Virus Infection	Hiv - [Human Immunodeficiency Virus Infection]
Hiv Positive Nos	Hiv Disease
Acquired Immune Deficiency Syndrome-Related Complex	Aids-Like Syndrome
Aids-Related Complex Nos	Arc - [Aids-Related Complex]
Immunodeficiency Due To Human Immunodeficiency Virus Infection	Unspecified Human Immunodeficiency Virus Disease
Hiv Disease Nos	Human Immunodeficiency Virus Positive Nos
Hiv Nos	Deficiency Of Complement Initial Pathway
Deficiency Of Complement Terminal Pathway	Cfdd - [Complement Factor D Deficiency]
Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency	Nonfamilial Hypogammaglobulinaemia
Common Variable Immune Deficiency	Nonfamilial Agammaglobulinaemia
Common Variable Agammaglobulinaemia	Agammaglobulinaemia Nos
Agammaglobulinaemia Antibody Deficiency Syndrome	Hypogammaglobulinaemia Antibody Deficiency Syndrome
Acquired Agammaglobulinaemia Nos	Hypogammaglobulinaemia Nos
Hyper Igm

Myelodysplastic Syndrome

Myelodysplastic Syndromes	Myelodysplasia
MDS	Myelodysplastic Syndrome Included
Myelodysplastic Syndrome, Susceptibility To, Included	Myelodysplastic Syndrome, Somatic
Myelodysplastic Syndrome, Susceptibility To

Leukoencephalopathy With Vanishing White Matter

Cree Leukoencephalopathy	Vanishing White Matter Disease
Ovarioleukodystrophy	Vanishing White Matter Leukodystrophy
Childhood Ataxia With Central Nervous System Hypomyelinization	Cach
Cach Syndrome	Myelinosis Centralis Diffusa
VWM	Cle
Childhood Ataxia With Central Nervous System Hypomyelination	Childhood Ataxia With Diffuse Central Nervous System Hypomyelination
Cach/Vwm	Cach/Vwm Syndrome
Childhood Ataxia With Central Nervous System Hypomyelination/Vanishing White Matter	Cree Leukoencehalopathy
Late Infantile Cach Syndrome	Juvenile Or Adult Cach Syndrome
Congenital Or Early Infantile Cach Syndrome	Leukodystrophy With Vanishing White Matter

Alzheimer Disease, Familial, 1

Alzheimer Disease	Alzheimer'S Disease
Presenile And Senile Dementia	AD1
Alzheimer Disease, Susceptibility To	Alzheimer Disease, Late-Onset, Susceptibility To
Alzheimer Disease 1, Familial	AD
Familial Alzheimer Disease	Alzheimer Disease, Late-Onset
Alzheimers Dementia	Alzheimer Dementia
Alzheimer Sclerosis	Alzheimer Syndrome
Alzheimer-Type Dementia	Dat
Primary Senile Degenerative Dementia	Sdat
Alzheimer Disease 1	Autosomal Dominant Alzheimer Disease
Early-Onset Alzheimer Disease With Cerebral Amyloid Angiopathy	Late Onset Alzheimer Disease
Alzheimers Disease	Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy
Late-Onset Alzheimers Disease	Alzheimer'S Disease Pathway Kegg
Dementia Due To Alzheimer'S Disease	Alzheimer Disease Type 1
Alzheimers

Amyotrophic Lateral Sclerosis 1

Amyotrophic Lateral Sclerosis	ALS
Lou Gehrig Disease	Amyotrophic Lateral Sclerosis Type 1
Charcot Disease	ALS1
Amyotrophic Lateral Sclerosis, Susceptibility To	Fals
Lou Gehrig'S Disease	Mnd
Motor Neuron Disease	Familial Amyotrophic Lateral Sclerosis
Amyotrophic Lateral Sclerosis 1, Familial	Amyotrophic Lateral Sclerosis 1, Autosomal Dominant
Motor Neuron Disease, Bulbar	Motor Neurone Disease
Amyotrophic Lateral Sclerosis With Dementia	Dementia With Amyotrophic Lateral Sclerosis
Motor Neuron Disease, Amyotrophic Lateral Sclerosis	Sclerosis, Lateral, Amyotrophic
Sclerosis, Lateral, Amyotrophic, Type 1	Amyotrophic Sclerosis
Als - [Amyotrophic Lateral Sclerosis]	Wasting Palsy
Amyotrophic Paralysis	Amyotrophy Lateral Sclerosis
Wasting Paralysis	Spinal Progressive Amyotrophy
Progressive Atrophic Paralysis

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04243	EIF2AK2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Felis catus	EIF2AK2	VGNC	VGNC:69072
Mus musculus	EIF2AK2	MGD	MGI:1353449
Rattus norvegicus	EIF2AK2	RGD	RGD:3402
Macaca mulatta	EIF2AK2	VGNC	VGNC:106152
Canis familiaris	EIF2AK2	VGNC	VGNC:40257
Bos taurus	EIF2AK2	VGNC	VGNC:28381
Others	EIF2AK2	NCBI