1. GPCR/G Protein Neuronal Signaling
  2. mAChR
  3. AQ-RA 721

AQ-RA 721 is a muscarinic receptor antagonist with differential affinity for the m4 and M2 sites, which can be used to characterize muscarinic receptor subtypes. Other muscarinic receptor antagonists have differential affinity for the M1 (rat cerebral cortex), M2 (rat heart), M3 (rat submandibular gland), m4 (receptor expressed in Chinese hamster ovary cells transfected with CHO), and guinea pig uterine smooth muscle at the muscarinic binding site.

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AQ-RA 721 Chemical Structure

AQ-RA 721 Chemical Structure

CAS No. : 139051-89-1

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Description

AQ-RA 721 is a muscarinic receptor antagonist with differential affinity for the m4 and M2 sites, which can be used to characterize muscarinic receptor subtypes. Other muscarinic receptor antagonists have differential affinity for the M1 (rat cerebral cortex), M2 (rat heart), M3 (rat submandibular gland), m4 (receptor expressed in Chinese hamster ovary cells transfected with CHO), and guinea pig uterine smooth muscle at the muscarinic binding site[1].

Molecular Weight

361.44

Formula

C22H23N3O2

CAS No.
SMILES

O=C(C(C1=CC=CC=C12)C3=CC=CC=C3NC2=O)NC4CN5CCC4CC5

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

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AQ-RA 721 Related Classifications

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Product Name:
AQ-RA 721
Cat. No.:
HY-126862
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