2. Metabolic Enzyme/Protease
  3. Liposome
  4. ATX-002

ATX-002 is an ionizable cationic lipid for RNA drug delivery. The calculated pKa (c-pKa) and measured pKa values for ATX-002 are 8.68 and 6.03, respectively.

For research use only. We do not sell to patients.

ATX-002 Chemical Structure

ATX-002 Chemical Structure

CAS No. : 1777792-34-3

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1 mg USD 208 In-stock
5 mg USD 520 In-stock
10 mg USD 820 In-stock
25 mg USD 1650 In-stock
50 mg USD 2650 In-stock
100 mg USD 4300 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

ATX-002 is an ionizable cationic lipid for RNA drug delivery. The calculated pKa (c-pKa) and measured pKa values for ATX-002 are 8.68 and 6.03, respectively[1].

Molecular Weight

681.06

Formula

C39H72N2O5S
CAS No.
Appearance

Oil

Color

Light yellow to yellow

SMILES

CN(C)CCSC(N(CCCCCCCC(OC/C=C\CCCCCC)=O)CCCCCCCC(OC/C=C\CCCCCC)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 25 mg/mL (36.71 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4683 mL 7.3415 mL 14.6830 mL
5 mM 0.2937 mL 1.4683 mL 2.9366 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Concentration (final)

C2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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g

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Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥98.0%

COA (238 KB) HNMR (119 KB) MS (95 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4683 mL 7.3415 mL 14.6830 mL 36.7075 mL
5 mM 0.2937 mL 1.4683 mL 2.9366 mL 7.3415 mL
10 mM 0.1468 mL 0.7341 mL 1.4683 mL 3.6707 mL
15 mM 0.0979 mL 0.4894 mL 0.9789 mL 2.4472 mL
20 mM 0.0734 mL 0.3671 mL 0.7341 mL 1.8354 mL
25 mM 0.0587 mL 0.2937 mL 0.5873 mL 1.4683 mL
30 mM 0.0489 mL 0.2447 mL 0.4894 mL 1.2236 mL
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ATX-002 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ATX-0021777792-34-3ATX002ATX 002LiposomeInhibitorinhibitorinhibit

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