2. Cell Cycle/DNA Damage Vitamin D Related/Nuclear Receptor Metabolic Enzyme/Protease
  3. PPAR
  4. AZD4619

AZD4619 is an orally active, selective peroxisome proliferator-activated receptor α (PPARα) agonist. AZD4619 increases alanine aminotransferase 1 (ALT1) protein expression in a dose-dependent manner in human, but not in rat primary hepatocytes. AZD4619 is a lipid-lowering drug.

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AZD4619 Chemical Structure

AZD4619 Chemical Structure

CAS No. : 1067247-60-2

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AZD4619 Related Antibodies

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Description

AZD4619 is an orally active, selective peroxisome proliferator-activated receptor α (PPARα) agonist. AZD4619 increases alanine aminotransferase 1 (ALT1) protein expression in a dose-dependent manner in human, but not in rat primary hepatocytes. AZD4619 is a lipid-lowering drug[1][2].

IC50 & Target[1]

PPARα

 

Molecular Weight

518.60

Formula

C25H26O8S2
CAS No.
SMILES

OC(C=C1)=CC=C1CCS[C@H](C(O)=O)CC2=CC=C(C=C2)CCOC3=CC=C(C=C3)OS(=O)(O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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AZD4619 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

AZD46191067247-60-2AZD 4619AZD-4619PPARPeroxisome proliferator-activated receptorsOrallyperoxisome proliferator-activated receptorPPARαalanine aminotransferaseALT1lipid-loweringInhibitorinhibitorinhibit

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