2. Cell Cycle/DNA Damage Neuronal Signaling Epigenetics
  3. HDAC Cholinesterase (ChE)
  4. BChE/HDAC6-IN-1

BChE/HDAC6-IN-1 is a potent and selective dual BChE/HDAC6 inhibitor with IC50 values of 4 and 8.9 nM, respectively. BChE/HDAC6-IN-1 ameliorates the cognitive impairment in an Aβ1–42-induced mouse model and has the potental for AD research.

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BChE/HDAC6-IN-1 Chemical Structure

BChE/HDAC6-IN-1 Chemical Structure

CAS No. : 2925457-27-6

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Description

BChE/HDAC6-IN-1 is a potent and selective dual BChE/HDAC6 inhibitor with IC50 values of 4 and 8.9 nM, respectively. BChE/HDAC6-IN-1 ameliorates the cognitive impairment in an Aβ1–42-induced mouse model and has the potental for AD research[1].

Molecular Weight

601.74

Formula

C34H43N5O5
CAS No.
SMILES

O=C(NCC1=CC=CC=C1CN(CC)CC)C2=CC(NC(C3=CC(NC(CCCCCCC(NO)=O)=O)=CC=C3)=O)=CC=C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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BChE/HDAC6-IN-1 Related Classifications

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Keywords:

BChE/HDAC6-IN-12925457-27-6HDACCholinesterase (ChE)Histone deacetylasesAlzheimer’s diseasebutyrylcholinesteraseneuroprotectioncentral nervous systemADInhibitorinhibitorinhibit

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