2. GPCR/G Protein Neuronal Signaling
  3. Opioid Receptor
  4. β-Casomorphin, bovine TFA

β-Casomorphin, bovine TFA  (Synonyms: β-Casomorphin-7 (bovine) (TFA); Bovine β-casomorphin-7 TFA)

Cat. No.: HY-P0179A
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β-Casomorphin, bovine TFA (β-Casomorphin-7 (bovine) TFA) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay.

For research use only. We do not sell to patients.

β-Casomorphin, bovine TFA Chemical Structure

β-Casomorphin, bovine TFA Chemical Structure

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β-Casomorphin, bovine TFA Related Antibodies

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Description

β-Casomorphin, bovine TFA (β-Casomorphin-7 (bovine) TFA) is a opioid peptide with an IC50 of 14 μM in an Opioid receptors binding assay[1].

IC50 & Target

IC50: 14 μM (Opioid receptor)[1]
In Vitro

β-Casomorphin, bovine TFA (0.1μM; 30 minutes-24 hours) stimulates the secretion of mucin in DHE Cells after 8 h of treatment[2].
β-Casomorphin, bovine TFA (0.1μM; 24 hours) induces an increase in rMuc2 and rMuc3 mRNA levels[2].
β-Casomorphin, bovine TFA does not modify the expression of rMuc1, rMuc4, and rMuc5AC[2].
β-Casomorphin, bovine TFA (0.1μM; 24 hours) stimulates MUC5AC expression and mucin Secretion in HT29-MTX Cells (human)[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

β-Casomorphin, bovine TFA Related Antibodies
In Vivo

β-Casomorphin, bovine TFA (7.5×10?6 mol/day/kg ; i.g.; for 30 days) increases plasma insulin and decreased plasma glucagon of diabetic rats[3].
β-Casomorphin, bovine TFA (7.5×10?6 mol/day/kg ; i.g.; for 30 days) alters the changes of SOD, GPx, T-AOC, MDA and H2O2 in the kidney of diabetic rats[3].
β-Casomorphin, bovine TFA (7.5×10?6 mol/day/kg ; i.g.; for 30 days) reduces MDA (significantly) and H2O2 (non-significantly) level in the kidney compared to the diabetic rats[3].
β-Casomorphin, bovine TFA (7.5×10?6 mol/day/kg ; i.g.; for 30 days) alleviates high glucose-induced decreasement in SOD and GPx activity, increasement in MDA contents in the NRK-52E cells[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley (SD) rats (200 g±10 g)[3]
Dosage: 7.5×10−6 mol/day/kg
Administration: Oral gavage; for 30 days
Result: Increased plasma insulin and decreased plasma glucagon of diabetic rats.
Molecular Weight

903.94

Formula

C43H56F3N7O11
Sequence

Tyr-Pro-Phe-Pro-Gly-Pro-Ile
Sequence Shortening

YPFPGPI
SMILES

O=C(N(CCC1)[C@@H]1C(NCC(N(CCC2)[C@@H]2C(N[C@H](C(O)=O)[C@@H](C)CC)=O)=O)=O)[C@@H](NC([C@H](CCC3)N3C([C@@H](N)CC4=CC=C(O)C=C4)=O)=O)CC5=CC=CC=C5.OC(C(F)(F)F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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β-Casomorphin, bovine TFA Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

β-Casomorphin, bovineβ-Casomorphin-7 (bovine) (TFA)Bovine β-casomorphin-7Opioid ReceptoropioidpeptidemucinInhibitorinhibitorinhibit

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