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  6. Bisabolol oxide A

Bisabolol oxide A possesses antihyperalgesic and antiedematous effects with oral activity.

For research use only. We do not sell to patients.

Bisabolol oxide A Chemical Structure

Bisabolol oxide A Chemical Structure

CAS No. : 22567-36-8

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1 mg USD 85 In-stock
5 mg USD 210 In-stock
10 mg USD 340 In-stock
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Based on 1 publication(s) in Google Scholar

Bisabolol oxide A Related Antibodies

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Description

Bisabolol oxide A possesses antihyperalgesic and antiedematous effects with oral activity[1].

Molecular Weight

238.37

Formula

C15H26O2
CAS No.
Appearance

Liquid (Density: 0.982±0.06 g/cm3)

Color

Colorless to light yellow

SMILES

C[C@@]1(OC(C)([C@H](CC1)O)C)[C@@]2([H])CCC(C)=CC2
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (839.03 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.1952 mL 20.9758 mL 41.9516 mL
5 mM 0.8390 mL 4.1952 mL 8.3903 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for in vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

  • Protocol 1

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 5 mg/mL (20.98 mM); Clear solution

    This protocol yields a clear solution of ≥ 5 mg/mL (saturation unknown).

    Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (50.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

    Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
%
DMSO +
% 
+
%
Tween-80 +
%
Saline
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Calculation results:
Working solution concentration: mg/mL
Method for preparing stock solution: mg drug dissolved in μL  DMSO (Stock solution concentration: mg/mL).

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only. If necessary, please contact MedChemExpress (MCE).
Method for preparing in vivo working solution for animal experiments: Take μL DMSO stock solution, add μL . μL , mix evenly, next add μL Tween 80, mix evenly, then add μL Saline.
 If the continuous dosing period exceeds half a month, please choose this protocol carefully.
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.1952 mL 20.9758 mL 41.9516 mL 104.8790 mL
5 mM 0.8390 mL 4.1952 mL 8.3903 mL 20.9758 mL
10 mM 0.4195 mL 2.0976 mL 4.1952 mL 10.4879 mL
15 mM 0.2797 mL 1.3984 mL 2.7968 mL 6.9919 mL
20 mM 0.2098 mL 1.0488 mL 2.0976 mL 5.2439 mL
25 mM 0.1678 mL 0.8390 mL 1.6781 mL 4.1952 mL
30 mM 0.1398 mL 0.6992 mL 1.3984 mL 3.4960 mL
40 mM 0.1049 mL 0.5244 mL 1.0488 mL 2.6220 mL
50 mM 0.0839 mL 0.4195 mL 0.8390 mL 2.0976 mL
60 mM 0.0699 mL 0.3496 mL 0.6992 mL 1.7480 mL
80 mM 0.0524 mL 0.2622 mL 0.5244 mL 1.3110 mL
100 mM 0.0420 mL 0.2098 mL 0.4195 mL 1.0488 mL
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Bisabolol oxide A Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Bisabolol oxide A22567-36-8OthersInhibitorinhibitorinhibit

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