2. Epigenetics
  3. Histone Methyltransferase
  4. BIX-01338 hydrate

BIX-01338 hydrate is a histone lysine methyltransferase inhibitor.

For research use only. We do not sell to patients.

BIX-01338 hydrate Chemical Structure

BIX-01338 hydrate Chemical Structure

CAS No. : 1228184-65-3

Size Price Stock Quantity
5 mg USD 425 In-stock
10 mg USD 680 In-stock
25 mg USD 1300 In-stock
50 mg USD 2050 In-stock
100 mg USD 3300 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

BIX-01338 hydrate Related Antibodies

Top Publications Citing Use of Products

View All Histone Methyltransferase Isoform Specific Products:

View All Isoforms
EZH1 EZH2 DOT1L SMYD2 SMYD3 SUV39H2/KMT1B EHMT2/G9a/KMT1C EHMT1/GLP/KMT1D SETDB1/KMT2G SETD2/KMT3A NSD2/MMSET/WHSC1 SETD7/KMT7 SETD8/KMT5A PRMT1 PRMT3 PRMT4 PRMT5 PRMT6 PRMT7 PRMT8

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Description

BIX-01338 hydrate is a histone lysine methyltransferase inhibitor.

IC50 & Target

Histone lysine methyltransferase[1]
Molecular Weight

621.56

Formula

C32H26F3N3O7
CAS No.
Appearance

Solid

Color

Light blue to blue

SMILES

O=C(C1=CC=C2C(N=C(NC(C3=CC=C(C(F)(F)F)C=C3)=O)N2CCC4=CC=C(OC(C5=CC=C(OC)C=C5)=O)C=C4)=C1)O.O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 200 mg/mL (321.77 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.6089 mL 8.0443 mL 16.0886 mL
5 mM 0.3218 mL 1.6089 mL 3.2177 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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mg/kg

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g

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(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.6089 mL 8.0443 mL 16.0886 mL 40.2214 mL
5 mM 0.3218 mL 1.6089 mL 3.2177 mL 8.0443 mL
10 mM 0.1609 mL 0.8044 mL 1.6089 mL 4.0221 mL
15 mM 0.1073 mL 0.5363 mL 1.0726 mL 2.6814 mL
20 mM 0.0804 mL 0.4022 mL 0.8044 mL 2.0111 mL
25 mM 0.0644 mL 0.3218 mL 0.6435 mL 1.6089 mL
30 mM 0.0536 mL 0.2681 mL 0.5363 mL 1.3407 mL
40 mM 0.0402 mL 0.2011 mL 0.4022 mL 1.0055 mL
50 mM 0.0322 mL 0.1609 mL 0.3218 mL 0.8044 mL
60 mM 0.0268 mL 0.1341 mL 0.2681 mL 0.6704 mL
80 mM 0.0201 mL 0.1006 mL 0.2011 mL 0.5028 mL
100 mM 0.0161 mL 0.0804 mL 0.1609 mL 0.4022 mL
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BIX-01338 hydrate Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BIX-013381228184-65-3BIX01338BIX 01338Histone MethyltransferaseInhibitorinhibitorinhibit

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