2. PROTAC Stem Cell/Wnt Cell Cycle/DNA Damage
  3. Molecular Glues Ligands for E3 Ligase Casein Kinase
  4. BMS-986397

For research use only. We do not sell to patients.

BMS-986397 Chemical Structure

BMS-986397 Chemical Structure

CAS No. : 2564486-44-6

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BMS-986397 Related Antibodies

Top Publications Citing Use of Products

View All Ligands for E3 Ligase Isoform Specific Products:

View All Isoforms
von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1

View All Casein Kinase Isoform Specific Products:

View All Isoforms
CK1 CK2

  • Biological Activity

  • Purity & Documentation

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IC50 & Target

Cereblon

 

Molecular Weight

480.82

Formula

C21H16ClF3N4O4
CAS No.
SMILES

O=C1CC[C@@H](C(N1)=O)N2CC3=C(C2=O)C=CC(C(N[C@@H](C(F)(F)F)C4=NC=CC=C4Cl)=O)=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (207.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.0798 mL 10.3989 mL 20.7978 mL
5 mM 0.4160 mL 2.0798 mL 4.1596 mL
View the Complete Stock Solution Preparation Table

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.0798 mL 10.3989 mL 20.7978 mL 51.9945 mL
5 mM 0.4160 mL 2.0798 mL 4.1596 mL 10.3989 mL
10 mM 0.2080 mL 1.0399 mL 2.0798 mL 5.1995 mL
15 mM 0.1387 mL 0.6933 mL 1.3865 mL 3.4663 mL
20 mM 0.1040 mL 0.5199 mL 1.0399 mL 2.5997 mL
25 mM 0.0832 mL 0.4160 mL 0.8319 mL 2.0798 mL
30 mM 0.0693 mL 0.3466 mL 0.6933 mL 1.7332 mL
40 mM 0.0520 mL 0.2600 mL 0.5199 mL 1.2999 mL
50 mM 0.0416 mL 0.2080 mL 0.4160 mL 1.0399 mL
60 mM 0.0347 mL 0.1733 mL 0.3466 mL 0.8666 mL
80 mM 0.0260 mL 0.1300 mL 0.2600 mL 0.6499 mL
100 mM 0.0208 mL 0.1040 mL 0.2080 mL 0.5199 mL
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BMS-986397 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BMS-9863972564486-44-6BMS986397BMS 986397Molecular GluesLigands for E3 LigaseCasein KinaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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