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  3. Fluorescent Dye
  4. Boc-Leu-Lys-Arg-AMC

Boc-Leu-Lys-Arg-AMC is a fluorogenic substrate for the Kex2 endoprotease.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Boc-Leu-Lys-Arg-AMC Chemical Structure

Boc-Leu-Lys-Arg-AMC Chemical Structure

CAS No. : 109358-47-6

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5 mg USD 110 In-stock
10 mg USD 175 In-stock
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Based on 1 publication(s) in Google Scholar

Boc-Leu-Lys-Arg-AMC Related Antibodies

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Description

Boc-Leu-Lys-Arg-AMC is a fluorogenic substrate for the Kex2 endoprotease[1].

IC50 & Target

others
Molecular Weight

672.82

Formula

C33H52N8O7
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

{Boc-Leu}-Lys-{Arg-AMC}
Sequence Shortening

{Boc-Leu}-K-{Arg-AMC}
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (148.63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4863 mL 7.4314 mL 14.8628 mL
5 mM 0.2973 mL 1.4863 mL 2.9726 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4863 mL 7.4314 mL 14.8628 mL 37.1570 mL
5 mM 0.2973 mL 1.4863 mL 2.9726 mL 7.4314 mL
10 mM 0.1486 mL 0.7431 mL 1.4863 mL 3.7157 mL
15 mM 0.0991 mL 0.4954 mL 0.9909 mL 2.4771 mL
20 mM 0.0743 mL 0.3716 mL 0.7431 mL 1.8579 mL
25 mM 0.0595 mL 0.2973 mL 0.5945 mL 1.4863 mL
30 mM 0.0495 mL 0.2477 mL 0.4954 mL 1.2386 mL
40 mM 0.0372 mL 0.1858 mL 0.3716 mL 0.9289 mL
50 mM 0.0297 mL 0.1486 mL 0.2973 mL 0.7431 mL
60 mM 0.0248 mL 0.1239 mL 0.2477 mL 0.6193 mL
80 mM 0.0186 mL 0.0929 mL 0.1858 mL 0.4645 mL
100 mM 0.0149 mL 0.0743 mL 0.1486 mL 0.3716 mL
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Boc-Leu-Lys-Arg-AMC Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Boc-Leu-Lys-Arg-AMC109358-47-6Fluorescent DyeKex2 Endoprotease SubstrateInhibitorinhibitorinhibit

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