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C/EBPα inducer 1 (compound 78) is a potent inducer of C/EBPα and myeloid differentiation.

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C/EBPα inducer 1 Chemical Structure

C/EBPα inducer 1 Chemical Structure

CAS No. : 2374285-52-4

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Based on 1 publication(s) in Google Scholar

C/EBPα inducer 1 Related Antibodies

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Description

C/EBPα inducer 1 (compound 78) is a potent inducer of C/EBPα and myeloid differentiation[1].

In Vitro

C/EBPα inducer 1 (compound 78, 3 μM) causes myeloid differentiation differentiation[1].
C/EBPα inducer 1 (compound 78) increases the expression of the neutrophil differentiation surface marker CD11b[1].
C/EBPα inducer 1 (compound 78) induces the expression of the neutrophil differentiation surface marker CD11b and upregulation of CEBPA and its downstream targets[1].
C/EBPα inducer 1 (compound 78) can upregulate G-CSF receptors, and render leukemic cells more sensitive to G-CSF stimulation[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

C/EBPα inducer 1 Related Antibodies
Molecular Weight

377.33

Formula

C20H12FN3O4
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C1N(C2=CC=CC=C2)C(/C=C/C3=CC=C([N+]([O-])=O)O3)=NC4=CC=C(F)C=C41
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 6.25 mg/mL (16.56 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6502 mL 13.2510 mL 26.5020 mL
5 mM 0.5300 mL 2.6502 mL 5.3004 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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This equation is commonly abbreviated as: C1V1 = C2V2

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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6502 mL 13.2510 mL 26.5020 mL 66.2550 mL
5 mM 0.5300 mL 2.6502 mL 5.3004 mL 13.2510 mL
10 mM 0.2650 mL 1.3251 mL 2.6502 mL 6.6255 mL
15 mM 0.1767 mL 0.8834 mL 1.7668 mL 4.4170 mL
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C/EBPα inducer 1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

C/EBPα inducer 12374285-52-4OthersInhibitorinhibitorinhibit

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