2. Cell Cycle/DNA Damage
  3. Topoisomerase
  4. 261766-29-4

261766-29-4

N-(3-Pyridyl)indomethacinamide Chemical Structure

261766-29-4

Chemical Structure

  • N-(3-Pyridyl)indomethacinamide
  • CAS No: 261766-29-4
    Formula: C24H20ClN3O3
    Molecular Weight: 433.89
  • IUPAC Name: 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)-N-(pyridin-3-yl)acetamide
  • InChIKey: DTAPHQYAZUTCIG-UHFFFAOYSA-N
  • SMILES: O=C(N1C2=C(C(CC(NC3=CC=CN=C3)=O)=C1C)C=C(OC)C=C2)C4=CC=C(C=C4)Cl

Biological Activity: N-(3-Pyridyl)indomethacinamide is a derivative of Indomethacin (HY-14397). N-(3-Pyridyl)indomethacinamide is a COX2 inhibitor[1].

Cat. No. Product Name Purity Description
HY-N0394S3 L-Cystine-34S2 ≥98.0% L-Cystine-34S2 is the 34S-labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.
HY-N0394S4 L-Cystine-3,3'-13C2 99.0% L-Cystine-3,3'-13C2 is the 13C labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.
HY-N0394S2 (S)-L-Cystine-15N2 99.00% (S)-L-Cystine-15N2 is the 15N-labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.
HY-N0394S1 L-Cystine-d4 ≥98.0% L-Cystine-d4 is the deuterium labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.
HY-N0394R L-Cystine (Standard) ≥98% L-Cystine (Standard) is the analytical standard of L-Cystine. This product is intended for research and analytical applications. L-Cystine, the extracellular form of L-Cysteine (HY-Y0337), is a nutritionally dispensable semiessential sulfur-containing amino acid, occurring in proteins of plants and animals. L-Cystine induces Nrf2 protein elevation in a Keap1 (HY-P75897)-dependent manner and activates Nrf2 transcription factor. L-cystine can elicit cytoprotection by reducing ROS generation and protecting against oxidant- or doxorubicin-induced apoptosis. The reduced reabsorption of L-Cystine in renal tubules and its poor solubility in urine are the important causes of cystine precipitation and cystine crystal formation eventually leading to kidney stones. L-Cystine combined with L-theanine (HY-15121) enhances the production of antigen-specific IgG by increasing glutathione (GSH) levels and T helper 2 (Th2) mediated responses in mice. L-Cystine is promising for research of cystinuria and cystinosis
HY-N0394 L-Cystine 99.84% L-Cystine is an orally active extracellular form of L-Cysteine (HY-Y0337), occurring in proteins of plants and animals. L-Cystine elevates Nrf2 protein expression and activates Nrf2 transcription factor. L-cystine reduces ROS generation and protects against oxidant- or Doxorubicin (HY-15142A)-induced apoptosis. L-Cystine combined with L-theanine (HY-15121) enhances the production of antigen-specific IgG by increasing glutathione (GSH) levels and T helper 2 (Th2) mediated responses in mice. L-Cystine is promising for research of cystinuria and kidney stones

References

[1]. Yan H, et al. The Antitumor Effects of α-Linolenic Acid. J Pers Med. 2024 Feb 28;14(3):260. doi: 10.3390/jpm14030260. [Content Brief]

Keywords:

N-(3-Pyridyl)indomethacinamide