2. Metabolic Enzyme/Protease
  3. Cathepsin
  4. Cathepsin X-IN-1

Cathepsin X-IN-1 (compound 25) is a potent Cathepsin X inhibitor with an IC50 of 7.13 µM. Cathepsin X-IN-1 decreases PC-3 cell migration with low cytotoxic.

For research use only. We do not sell to patients.

Cathepsin X-IN-1 Chemical Structure

Cathepsin X-IN-1 Chemical Structure

CAS No. : 2418577-51-0

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5 mg USD 120 In-stock
10 mg USD 200 In-stock
25 mg USD 340 In-stock
50 mg USD 500 In-stock
100 mg USD 750 In-stock
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Based on 1 publication(s) in Google Scholar

Cathepsin X-IN-1 Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE Cathepsin X-IN-1

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View All Isoforms
Cathepsin B Cathepsin C Cathepsin D Cathepsin E Cathepsin K Cathepsin L Cathepsin S

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Description

Cathepsin X-IN-1 (compound 25) is a potent Cathepsin X inhibitor with an IC50 of 7.13 µM. Cathepsin X-IN-1 decreases PC-3 cell migration with low cytotoxic[1].

IC50 & Target

IC50: 7.13 µM (Cathepsin X)[1]
Molecular Weight

315.35

Formula

C15H13N3O3S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

N#CCN1C=CN=C1SCC(C2=CC3=C(OCCO3)C=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 100 mg/mL (317.11 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H2O : 4.85 mg/mL (15.38 mM; ultrasonic and warming and adjust pH to 3 with HCl and heat to 60°C)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1711 mL 15.8554 mL 31.7108 mL
5 mM 0.6342 mL 3.1711 mL 6.3422 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / DMSO 1 mM 3.1711 mL 15.8554 mL 31.7108 mL 79.2770 mL
5 mM 0.6342 mL 3.1711 mL 6.3422 mL 15.8554 mL
10 mM 0.3171 mL 1.5855 mL 3.1711 mL 7.9277 mL
15 mM 0.2114 mL 1.0570 mL 2.1141 mL 5.2851 mL
DMSO 20 mM 0.1586 mL 0.7928 mL 1.5855 mL 3.9638 mL
25 mM 0.1268 mL 0.6342 mL 1.2684 mL 3.1711 mL
30 mM 0.1057 mL 0.5285 mL 1.0570 mL 2.6426 mL
40 mM 0.0793 mL 0.3964 mL 0.7928 mL 1.9819 mL
50 mM 0.0634 mL 0.3171 mL 0.6342 mL 1.5855 mL
60 mM 0.0529 mL 0.2643 mL 0.5285 mL 1.3213 mL
80 mM 0.0396 mL 0.1982 mL 0.3964 mL 0.9910 mL
100 mM 0.0317 mL 0.1586 mL 0.3171 mL 0.7928 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Cathepsin X-IN-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cathepsin X-IN-12418577-51-0CathepsinPC-3 cellsmigrationneurodegenerative diseaseslow cytotoxicInhibitorinhibitorinhibit

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