2. Cell Cycle/DNA Damage
  3. CDK
  4. CDK1-IN-2

CDK1-IN-2 is a CDK1 inhibitor (IC50: 5.8 μM).

For research use only. We do not sell to patients.

CDK1-IN-2 Chemical Structure

CDK1-IN-2 Chemical Structure

CAS No. : 220749-41-7

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1 mg USD 45 In-stock
5 mg USD 135 In-stock
10 mg USD 220 In-stock
25 mg USD 450 In-stock
50 mg USD 720 In-stock
100 mg USD 1150 In-stock
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Based on 1 publication(s) in Google Scholar

CDK1-IN-2 Related Antibodies

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Description

CDK1-IN-2 is a CDK1 inhibitor (IC50: 5.8 μM)[1].

IC50 & Target[1]

CDK1

5.8 μM (IC50)

In Vitro

CDK1-IN-2 (“CDK1 inhibitor 1”, 0-19.8 μM, 24 h) arrests HCT-116 cells in G2/M phase[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CDK1-IN-2 Related Antibodies
Molecular Weight

294.74

Formula

C17H11ClN2O
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

O=C1NC2=C(C=CC=C2)/C1=C\C3=C(Cl)NC4=C3C=CC=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : ≥ 250 mg/mL (848.21 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3928 mL 16.9641 mL 33.9282 mL
5 mM 0.6786 mL 3.3928 mL 6.7856 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.3928 mL 16.9641 mL 33.9282 mL 84.8205 mL
5 mM 0.6786 mL 3.3928 mL 6.7856 mL 16.9641 mL
10 mM 0.3393 mL 1.6964 mL 3.3928 mL 8.4821 mL
15 mM 0.2262 mL 1.1309 mL 2.2619 mL 5.6547 mL
20 mM 0.1696 mL 0.8482 mL 1.6964 mL 4.2410 mL
25 mM 0.1357 mL 0.6786 mL 1.3571 mL 3.3928 mL
30 mM 0.1131 mL 0.5655 mL 1.1309 mL 2.8274 mL
40 mM 0.0848 mL 0.4241 mL 0.8482 mL 2.1205 mL
50 mM 0.0679 mL 0.3393 mL 0.6786 mL 1.6964 mL
60 mM 0.0565 mL 0.2827 mL 0.5655 mL 1.4137 mL
80 mM 0.0424 mL 0.2121 mL 0.4241 mL 1.0603 mL
100 mM 0.0339 mL 0.1696 mL 0.3393 mL 0.8482 mL
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CDK1-IN-2 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CDK1-IN-2220749-41-7CDKCyclin dependent kinaseHCT-116 cellscancerInhibitorinhibitorinhibit

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