Chlormadinone acetate-d₆-1

Name: Chlormadinone acetate-d 6 -1
Brand: MedChemExpress
SKU: HY-B1095S1
Rating: 4.5 (1 reviews)

Cat. No.: HY-B1095S1 Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

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Chlormadinone acetate-d₆-1 is deuterium labeled Chlormadinone acetate.

For research use only. We do not sell to patients.

Chlormadinone acetate-d<sub>6</sub>-1 Chemical Structure

Chlormadinone acetate-d₆-1 Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 820	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of Chlormadinone acetate-d₆-1:

Chlormadinone acetate In-stock

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Chlormadinone acetate-d₆-1 is deuterium labeled Chlormadinone acetate.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

410.96

Formula

C₂₃H₂₃D₆ClO₄

Unlabeled CAS

302-22-7

Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](C(C([2H])([2H])[2H])=O)(OC(C)=O)CC[C@@]1([H])[C@]3([H])C=C(Cl)C4=C([2H])C(C([2H])([2H])C[C@]4(C)[C@@]3([H])CC2)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 10 mg/mL (24.33 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : 1 mg/mL (2.43 mM; ultrasonic and warming and heat to 80°C)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.4333 mL	12.1666 mL	24.3333 mL
5 mM	0.4867 mL	2.4333 mL	4.8667 mL
10 mM	0.2433 mL	1.2167 mL	2.4333 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (278 KB) SDS (251 KB)

COA (258 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O / H₂O / DMSO / DMSO	1 mM	2.4333 mL	12.1666 mL	24.3333 mL	60.8332 mL
DMSO / DMSO	5 mM	0.4867 mL	2.4333 mL	4.8667 mL	12.1666 mL
	10 mM	0.2433 mL	1.2167 mL	2.4333 mL	6.0833 mL
	15 mM	0.1622 mL	0.8111 mL	1.6222 mL	4.0555 mL
	20 mM	0.1217 mL	0.6083 mL	1.2167 mL	3.0417 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.