2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. Co 102862

Co 102862  (Synonyms: V 102862)

Cat. No.: HY-108504 Purity: 99.87%
COA Handling Instructions

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Co 102862 (V 102862) is a potent, broad-spectrum, state-dependent Na+ channel blocker. Co 102862 is also an orally active anticonvulsant.

For research use only. We do not sell to patients.

Co 102862 Chemical Structure

Co 102862 Chemical Structure

CAS No. : 181144-66-1

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 61 In-stock
Solution
10 mM * 1 mL in DMSO USD 61 In-stock
Solid
5 mg USD 55 In-stock
10 mg USD 90 In-stock
25 mg USD 180 In-stock
50 mg USD 280 In-stock
100 mg USD 450 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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  • Biological Activity

  • Purity & Documentation

  • References

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Description

Co 102862 (V 102862) is a potent, broad-spectrum, state-dependent Na+ channel blocker. Co 102862 is also an orally active anticonvulsant[1].

Molecular Weight

273.26

Formula

C14H12FN3O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

FC1=CC=C(OC2=CC=C(/C=N/NC(N)=O)C=C2)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 41.67 mg/mL (152.49 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6595 mL 18.2976 mL 36.5952 mL
5 mM 0.7319 mL 3.6595 mL 7.3190 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6595 mL 18.2976 mL 36.5952 mL 91.4880 mL
5 mM 0.7319 mL 3.6595 mL 7.3190 mL 18.2976 mL
10 mM 0.3660 mL 1.8298 mL 3.6595 mL 9.1488 mL
15 mM 0.2440 mL 1.2198 mL 2.4397 mL 6.0992 mL
20 mM 0.1830 mL 0.9149 mL 1.8298 mL 4.5744 mL
25 mM 0.1464 mL 0.7319 mL 1.4638 mL 3.6595 mL
30 mM 0.1220 mL 0.6099 mL 1.2198 mL 3.0496 mL
40 mM 0.0915 mL 0.4574 mL 0.9149 mL 2.2872 mL
50 mM 0.0732 mL 0.3660 mL 0.7319 mL 1.8298 mL
60 mM 0.0610 mL 0.3050 mL 0.6099 mL 1.5248 mL
80 mM 0.0457 mL 0.2287 mL 0.4574 mL 1.1436 mL
100 mM 0.0366 mL 0.1830 mL 0.3660 mL 0.9149 mL
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Co 102862 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Co 102862181144-66-1V 102862Co102862Co-102862V102862V-102862Sodium ChannelNa channelsNa+ channelsbroad-spectrumstate-dependentorally activeanticonvulsantInhibitorinhibitorinhibit

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