2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite Fatty Acid Synthase (FASN)
  4. Coenzyme A sodium

Coenzyme A (CoASH) sodium is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids.

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Coenzyme A sodium Chemical Structure

Coenzyme A sodium Chemical Structure

CAS No. : 55672-92-9

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Based on 1 publication(s) in Google Scholar

Other Forms of Coenzyme A sodium:

Coenzyme A sodium Related Antibodies

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Description

Coenzyme A (CoASH) sodium is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids[1].

IC50 & Target

Human Endogenous Metabolite

 

Clinical Trial
Molecular Weight

833.48

Formula

C21H33N7Na3O16P3S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC([C@H](C(NCCC(NCCS)=O)=O)O)(C)COP(OP(OC[C@H]1O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@H](O)[C@@H]1OP(O)(O[Na])=O)(O[Na])=O)(O[Na])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (59.99 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1998 mL 5.9989 mL 11.9979 mL
5 mM 0.2400 mL 1.1998 mL 2.3996 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.46%

SDS (393 KB)

COA (247 KB) HNMR (306 KB) CNMR (259 KB) RP-HPLC (205 KB) MS (68 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.1998 mL 5.9989 mL 11.9979 mL 29.9947 mL
5 mM 0.2400 mL 1.1998 mL 2.3996 mL 5.9989 mL
10 mM 0.1200 mL 0.5999 mL 1.1998 mL 2.9995 mL
15 mM 0.0800 mL 0.3999 mL 0.7999 mL 1.9996 mL
20 mM 0.0600 mL 0.2999 mL 0.5999 mL 1.4997 mL
25 mM 0.0480 mL 0.2400 mL 0.4799 mL 1.1998 mL
30 mM 0.0400 mL 0.2000 mL 0.3999 mL 0.9998 mL
40 mM 0.0300 mL 0.1500 mL 0.2999 mL 0.7499 mL
50 mM 0.0240 mL 0.1200 mL 0.2400 mL 0.5999 mL
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Coenzyme A sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Coenzyme A55672-92-9Endogenous MetaboliteFatty Acid Synthase (FASN)ubiquitous essential cofactoracyl group carriercitric acid cyclefatty acid metabolismmetabolismInhibitorinhibitorinhibit

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Coenzyme A sodium
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SAFETY DATA SHEET (SDS)

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