2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite Fatty Acid Synthase (FASN)
  4. Coenzyme A trilithium

Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids.

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Coenzyme A trilithium Chemical Structure

Coenzyme A trilithium Chemical Structure

CAS No. : 18439-24-2

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Based on 1 publication(s) in Google Scholar

Other Forms of Coenzyme A trilithium:

Coenzyme A trilithium Related Antibodies

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Description

Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids[1].

IC50 & Target

Human Endogenous Metabolite

 

Clinical Trial
Molecular Weight

785.33

Formula

C21H33Li3N7O16P3S
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CC([C@H](C(NCCC(NCCS)=O)=O)O)(C)COP(OP(OC[C@H]1O[C@@H](N2C3=NC=NC(N)=C3N=C2)[C@H](O)[C@@H]1OP(O)(O[Li])=O)(O[Li])=O)(O[Li])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (159.17 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2734 mL 6.3668 mL 12.7335 mL
5 mM 0.2547 mL 1.2734 mL 2.5467 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

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g

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(per animal)

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 1.2734 mL 6.3668 mL 12.7335 mL 31.8338 mL
5 mM 0.2547 mL 1.2734 mL 2.5467 mL 6.3668 mL
10 mM 0.1273 mL 0.6367 mL 1.2734 mL 3.1834 mL
15 mM 0.0849 mL 0.4245 mL 0.8489 mL 2.1223 mL
20 mM 0.0637 mL 0.3183 mL 0.6367 mL 1.5917 mL
25 mM 0.0509 mL 0.2547 mL 0.5093 mL 1.2734 mL
30 mM 0.0424 mL 0.2122 mL 0.4245 mL 1.0611 mL
40 mM 0.0318 mL 0.1592 mL 0.3183 mL 0.7958 mL
50 mM 0.0255 mL 0.1273 mL 0.2547 mL 0.6367 mL
60 mM 0.0212 mL 0.1061 mL 0.2122 mL 0.5306 mL
80 mM 0.0159 mL 0.0796 mL 0.1592 mL 0.3979 mL
100 mM 0.0127 mL 0.0637 mL 0.1273 mL 0.3183 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Coenzyme A trilithium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Coenzyme A trilithium18439-24-2Endogenous MetaboliteFatty Acid Synthase (FASN)ubiquitous essential cofactoracyl group carriercitric acid cyclefatty acid metabolismmetabolismInhibitorinhibitorinhibit

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