1. GPCR/G Protein Neuronal Signaling
  2. Somatostatin Receptor
  3. Cortistatin-17 (human)

Cortistatin-17 (human) is a somatostatin neuropeptide with potential for studying diseases such as cancer, inflammation, autoimmunity, fibrosis, and pain.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Cortistatin-17 (human) Chemical Structure

Cortistatin-17 (human) Chemical Structure

CAS No. : 189450-19-9

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Description

Cortistatin-17 (human) is a somatostatin neuropeptide with potential for studying diseases such as cancer, inflammation, autoimmunity, fibrosis, and pain[1][2].

Molecular Weight

2151.49

Formula

C96H139N27O24S3

CAS No.
Appearance

Solid

Color

White to off-white

Sequence

Asp-Arg-Met-Pro-Cys-Arg-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Ser-Ser-Cys-Lys (Disulfide bridge: Cys5-Cys16)

Sequence Shortening

DRMPCRNFFWKTFSSCK (Disulfide bridge: Cys5-Cys16)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (46.48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.4648 mL 2.3240 mL 4.6479 mL
5 mM 0.0930 mL 0.4648 mL 0.9296 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.4648 mL 2.3240 mL 4.6479 mL 11.6199 mL
5 mM 0.0930 mL 0.4648 mL 0.9296 mL 2.3240 mL
10 mM 0.0465 mL 0.2324 mL 0.4648 mL 1.1620 mL
15 mM 0.0310 mL 0.1549 mL 0.3099 mL 0.7747 mL
20 mM 0.0232 mL 0.1162 mL 0.2324 mL 0.5810 mL
25 mM 0.0186 mL 0.0930 mL 0.1859 mL 0.4648 mL
30 mM 0.0155 mL 0.0775 mL 0.1549 mL 0.3873 mL
40 mM 0.0116 mL 0.0581 mL 0.1162 mL 0.2905 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Cortistatin-17 (human)
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HY-P5011
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